Fibroblast Growth Factors
"Fibroblast Growth Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
Descriptor ID |
D005346
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MeSH Number(s) |
D12.644.276.624 D12.776.467.624 D23.529.624
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Concept/Terms |
Fibroblast Growth Factors- Fibroblast Growth Factors
- Growth Factors, Fibroblast
- Fibroblast Growth Factor
- Growth Factor, Fibroblast
- Fibroblast Growth Regulatory Factor
- DNA Synthesis Factor
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Below are MeSH descriptors whose meaning is more general than "Fibroblast Growth Factors".
Below are MeSH descriptors whose meaning is more specific than "Fibroblast Growth Factors".
This graph shows the total number of publications written about "Fibroblast Growth Factors" by people in this website by year, and whether "Fibroblast Growth Factors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1990 | 1 | 0 | 1 | 1999 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2006 | 2 | 0 | 2 | 2008 | 2 | 0 | 2 | 2009 | 0 | 1 | 1 | 2011 | 1 | 1 | 2 | 2012 | 1 | 1 | 2 |
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Below are the most recent publications written about "Fibroblast Growth Factors" by people in Profiles.
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Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK. TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: a new link in the FGF/BMP regulatory network. Differentiation. 2012 Apr; 83(4):210-9.
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King GD, Chen C, Huang MM, Zeldich E, Brazee PL, Schuman ER, Robin M, Cuny GD, Glicksman MA, Abraham CR. Identification of novel small molecules that elevate Klotho expression. Biochem J. 2012 Jan 01; 441(1):453-61.
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Samson SL, Sathyanarayana P, Jogi M, Gonzalez EV, Gutierrez A, Krishnamurthy R, Muthupillai R, Chan L, Bajaj M. Exenatide decreases hepatic fibroblast growth factor 21 resistance in non-alcoholic fatty liver disease in a mouse model of obesity and in a randomised controlled trial. Diabetologia. 2011 Dec; 54(12):3093-100.
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Li T, Holmstrom SR, Kir S, Umetani M, Schmidt DR, Kliewer SA, Mangelsdorf DJ. The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling. Mol Endocrinol. 2011 Jun; 25(6):1066-71.
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Fischer AJ, Scott MA, Ritchey ER, Sherwood P. Mitogen-activated protein kinase-signaling regulates the ability of Müller glia to proliferate and protect retinal neurons against excitotoxicity. Glia. 2009 Nov 01; 57(14):1538-52.
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Vaccarino FM, Grigorenko EL, Smith KM, Stevens HE. Regulation of cerebral cortical size and neuron number by fibroblast growth factors: implications for autism. J Autism Dev Disord. 2009 Mar; 39(3):511-20.
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Zhang J, Lin Y, Zhang Y, Lan Y, Lin C, Moon AM, Schwartz RJ, Martin JF, Wang F. Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. Development. 2008 Nov; 135(21):3611-22.
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Choi M, Moschetta A, Bookout AL, Peng L, Umetani M, Holmstrom SR, Suino-Powell K, Xu HE, Richardson JA, Gerard RD, Mangelsdorf DJ, Kliewer SA. Identification of a hormonal basis for gallbladder filling. Nat Med. 2006 Nov; 12(11):1253-5.
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Kharitonenkov A, Wroblewski VJ, Koester A, Chen YF, Clutinger CK, Tigno XT, Hansen BC, Shanafelt AB, Etgen GJ. The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21. Endocrinology. 2007 Feb; 148(2):774-81.
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Liu W, Selever J, Murali D, Sun X, Brugger SM, Ma L, Schwartz RJ, Maxson R, Furuta Y, Martin JF. Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15; 283(2):282-93.
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