 Ganglionic Blockers
"Ganglionic Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
| Descriptor ID |
D005730
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| MeSH Number(s) |
D27.505.696.663.050.340
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| Concept/Terms |
Ganglionic Blockers- Ganglionic Blockers
- Blockers, Ganglionic
- Blocking Agents, Ganglionic
- Agents, Ganglionic Blocking
- Ganglioplegic Agents
- Agents, Ganglioplegic
- Ganglionic Blockaders
- Blockaders, Ganglionic
- Ganglionic Blocking Agents
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Below are MeSH descriptors whose meaning is more general than "Ganglionic Blockers".
Below are MeSH descriptors whose meaning is more specific than "Ganglionic Blockers".
This graph shows the total number of publications written about "Ganglionic Blockers" by people in this website by year, and whether "Ganglionic Blockers" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 1 | 0 | 1 | | 1986 | 1 | 0 | 1 | | 1990 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ganglionic Blockers" by people in Profiles.
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Tallam LS, Jandhyala BS. Influence of plasma insulin levels on antinatriuretic and vasoconstrictor actions of angiotensin-II. Clin Exp Hypertens. 2003 May; 25(4):257-70.
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Hogan YH, Florent G, Hussain T, Alkadhi KA. Cyclic AMP antagonizes adenosine-induced inhibition of ganglionic transmission. Brain Res. 1998 Mar 23; 787(2):242-7.
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Subramony P, Dryer SE. The effects of innervation on the developmental expression of Ca(2+)-activated K+ currents in embryonic parasympathetic neurons are not activity-dependent. Brain Res Dev Brain Res. 1996 Jan 22; 91(1):149-52.
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Alkadhi KA, Bassey EI, Hogan YH. A comparative study of the actions of histamine H2 receptor antagonists on transmission in the isolated superior cervical ganglion of the rat. Neuropharmacology. 1990 Mar; 29(3):285-90.
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Cates LA, Li VS, Basrur JP, Alkadhi KA. 2,2'-Phthaloyl-,2,2'-isophthaloyl-, and 2,2'-terephthaloylbis[1,1,1-trimethylhydrazinium] dihydroxide, bis(inner salts): synthesis, partition coefficients, toxicity and effect on ganglionic transmission. J Pharm Sci. 1986 Apr; 75(4):407-9.
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Cates LA, Li VS, Saddawi BH, Alkadhi KA. Phosphorus-nitrogen compounds. 26. Phosphaminimides. 2. 2,2'-Phosphinylidenebis(1,1,1-trimethylhydrazinium) iodide inner salts as agents affecting ganglionic transmission. J Med Chem. 1985 May; 28(5):595-7.
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Alkadhi KA, McIsaac RJ. Ganglion blocking effects of streptomycin. Arch Int Pharmacodyn Ther. 1978 Mar; 232(1):58-67.
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Lokhandwala MF, Buckley JP, Jandhyala BS. Studies on the mechanism of the cardiovascualr effects of methyldopa. Eur J Pharmacol. 1976 May; 37(1):79-89.
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Alkadhi KA, McIsaac RJ. Differential blockade of ganglionic transmission by extract from venom gland of black widow spider (Latrodectus mactans). Toxicon. 1974 Dec; 12(6):643-8.
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Alkadhi KA, McIsaac RJ. Effect of preganglionic nerve stimulation on sensitivity of the superior cervical ganglion to nicotinic blocking agents. Br J Pharmacol. 1974 Aug; 51(4):533-9.
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