 Histamine H2 Antagonists
"Histamine H2 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
| Descriptor ID |
D006635
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| MeSH Number(s) |
D27.505.519.625.375.425.425 D27.505.696.577.375.425.425
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| Concept/Terms |
Histamine H2 Antagonists- Histamine H2 Antagonists
- Receptor Blockaders, H2
- Blockaders, Histamine H2 Receptor
- Histamine H2 Receptor Blockaders
- Histamine H2 Blockers
- Blockers, Histamine H2
- H2 Blockers, Histamine
- Receptor Antagonists, Histamine H2
- Histamine H2 Receptor Antagonists
- Antagonists, Histamine H2
- H2 Antagonists, Histamine
- H2 Receptor Blockaders
- Blockaders, H2 Receptor
- Antihistaminics, H2
- H2 Antihistaminics
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Below are MeSH descriptors whose meaning is more general than "Histamine H2 Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Histamine H2 Antagonists".
This graph shows the total number of publications written about "Histamine H2 Antagonists" by people in this website by year, and whether "Histamine H2 Antagonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histamine H2 Antagonists" by people in Profiles.
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Mach CM, Lapp EA, Weddle KJ, Hunter RJ, Burns KA, Parker C, Brown J, Smith JA. Adjunct Histamine Blockers as Premedications to Prevent Carboplatin Hypersensitivity Reactions. Pharmacotherapy. 2016 May; 36(5):482-7.
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Murray MJ. Suppression of gastric acidity in horses. J Am Vet Med Assoc. 1997 Jul 01; 211(1):37-40.
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Clark EA, Hill SJ. Sensitivity of histamine H3 receptor agonist-stimulated [35S]GTP gamma[S] binding to pertussis toxin. Eur J Pharmacol. 1996 Jan 25; 296(2):223-5.
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Nowak JZ, Sek B, D'Souza T, Dryer SE. Does histamine stimulate cyclic AMP formation in the avian pineal gland via a novel (non-H1, non-H2, non-H3) histamine receptor subtype. Neurochem Int. 1995 Dec; 27(6):519-26.
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Alkadhi KA, Bassey EI, Hogan YH. A comparative study of the actions of histamine H2 receptor antagonists on transmission in the isolated superior cervical ganglion of the rat. Neuropharmacology. 1990 Mar; 29(3):285-90.
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Furr MO, Murray MJ. Treatment of gastric ulcers in horses with histamine type 2 receptor antagonists. Equine Vet J Suppl. 1989 Jun; (7):77-9.
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Lokhandwala MF. Inhibition of sympathetic nervous system by histamine:studies with H1- and H2-receptor antagonists. J Pharmacol Exp Ther. 1978 Jul; 206(1):115-22.
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