Mast Cells
"Mast Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
Descriptor ID |
D008407
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MeSH Number(s) |
A11.329.427 A15.382.652
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Concept/Terms |
Mast Cells- Mast Cells
- Cell, Mast
- Cells, Mast
- Mast Cell
- Basophils, Tissue
- Basophil, Tissue
- Tissue Basophil
- Tissue Basophils
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Below are MeSH descriptors whose meaning is more general than "Mast Cells".
Below are MeSH descriptors whose meaning is more specific than "Mast Cells".
This graph shows the total number of publications written about "Mast Cells" by people in this website by year, and whether "Mast Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 1998 | 2 | 0 | 2 | 1999 | 2 | 0 | 2 | 2006 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2008 | 3 | 0 | 3 | 2009 | 0 | 1 | 1 | 2010 | 2 | 0 | 2 | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mast Cells" by people in Profiles.
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Christy AL, Walker ME, Hessner MJ, Brown MA. Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE. J Autoimmun. 2013 May; 42:50-61.
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Zemtsova IM, Heise N, Fröhlich H, Qadri SM, Kucherenko Y, Boini KM, Pearce D, Shumilina E, Lang F. Blunted IgE-mediated activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3. Am J Physiol Cell Physiol. 2010 Nov; 299(5):C1007-14.
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Sayed BA, Christy AL, Walker ME, Brown MA. Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment? J Immunol. 2010 Jun 15; 184(12):6891-900.
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Mathivanan S, Lim JW, Tauro BJ, Ji H, Moritz RL, Simpson RJ. Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics. 2010 Feb; 9(2):197-208.
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Brown MA, Sayed BA, Christy A. Mast cells and the adaptive immune response. J Clin Immunol. 2008 Nov; 28(6):671-6.
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Sayed BA, Christy A, Quirion MR, Brown MA. The master switch: the role of mast cells in autoimmunity and tolerance. Annu Rev Immunol. 2008; 26:705-39.
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Burns AR, Oliver JM, Pfeiffer JR, Wilson BS. Visualizing clathrin-mediated IgE receptor internalization by electron and atomic force microscopy. Methods Mol Biol. 2008; 440:235-45.
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Christy AL, Brown MA. The multitasking mast cell: positive and negative roles in the progression of autoimmunity. J Immunol. 2007 Sep 01; 179(5):2673-9.
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Frankel DJ, Pfeiffer JR, Surviladze Z, Johnson AE, Oliver JM, Wilson BS, Burns AR. Revealing the topography of cellular membrane domains by combined atomic force microscopy/fluorescence imaging. Biophys J. 2006 Apr 01; 90(7):2404-13.
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Frangogiannis NG, Burns AR, Michael LH, Entman ML. Histochemical and morphological characteristics of canine cardiac mast cells. Histochem J. 1999 Apr; 31(4):221-9.
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