 Spindle Apparatus
"Spindle Apparatus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microtubule structure that forms during CELL DIVISION. It consists of two SPINDLE POLES, and sets of MICROTUBULES that may include the astral microtubules, the polar microtubules, and the kinetochore microtubules.
| Descriptor ID |
D008941
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| MeSH Number(s) |
A11.284.430.214.190.750.820
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| Concept/Terms |
Meiotic Spindle Apparatus- Meiotic Spindle Apparatus
- Apparatus, Meiotic Spindle
- Spindle Apparatus, Meiotic
- Meiotic Spindle
- Meiotic Spindles
- Spindle, Meiotic
- Spindles, Meiotic
Mitotic Spindle Apparatus- Mitotic Spindle Apparatus
- Apparatus, Mitotic Spindle
- Mitotic Spindle
- Mitotic Spindles
- Spindle, Mitotic
- Spindles, Mitotic
- Spindle Apparatus, Mitotic
- Mitotic Apparatus
- Apparatus, Mitotic
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Below are MeSH descriptors whose meaning is more general than "Spindle Apparatus".
Below are MeSH descriptors whose meaning is more specific than "Spindle Apparatus".
This graph shows the total number of publications written about "Spindle Apparatus" by people in this website by year, and whether "Spindle Apparatus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spindle Apparatus" by people in Profiles.
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Hell MP, Duda M, Weber TC, Moch H, Krek W. Tumor suppressor VHL functions in the control of mitotic fidelity. Cancer Res. 2014 May 01; 74(9):2422-31.
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Zeng X, Sigoillot F, Gaur S, Choi S, Pfaff KL, Oh DC, Hathaway N, Dimova N, Cuny GD, King RW. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell. 2010 Oct 19; 18(4):382-95.
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Ebrahimi S, Fraval H, Murray M, Saint R, Gregory SL. Polo kinase interacts with RacGAP50C and is required to localize the cytokinesis initiation complex. J Biol Chem. 2010 Sep 10; 285(37):28667-73.
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Ha GH, Baek KH, Kim HS, Jeong SJ, Kim CM, McKeon F, Lee CW. p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation. Cancer Res. 2007 Aug 01; 67(15):7155-64.
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Baek KH, Shin HJ, Jeong SJ, Park JW, McKeon F, Lee CW, Kim CM. Caspases-dependent cleavage of mitotic checkpoint proteins in response to microtubule inhibitor. Oncol Res. 2005; 15(3):161-8.
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Shin HJ, Baek KH, Jeon AH, Park MT, Lee SJ, Kang CM, Lee HS, Yoo SH, Chung DH, Sung YC, McKeon F, Lee CW. Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Cancer Cell. 2003 Dec; 4(6):483-97.
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Baek KH, Shin HJ, Yoo JK, Cho JH, Choi YH, Sung YC, McKeon F, Lee CW. p53 deficiency and defective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest. J Leukoc Biol. 2003 Jun; 73(6):850-61.
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Heald R, McLoughlin M, McKeon F. Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase. Cell. 1993 Aug 13; 74(3):463-74.
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