Papaverine
"Papaverine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
| Descriptor ID |
D010208
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| MeSH Number(s) |
D03.132.098.666 D03.132.577.750 D03.438.531.085.666
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Papaverine".
Below are MeSH descriptors whose meaning is more specific than "Papaverine".
This graph shows the total number of publications written about "Papaverine" by people in this website by year, and whether "Papaverine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 |
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
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Below are the most recent publications written about "Papaverine" by people in Profiles.
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D'Souza T, Dryer SE. Effects of phosphodiesterase inhibitors and forskolin on cyclic GMP-activated channels in intact isolated cells of the chick pineal gland. Neurochem Int. 1995 Dec; 27(6):527-33.
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Akay M, Akay YM, Welkowitz W, Lewkowicz S. Investigating the effects of vasodilator drugs on the turbulent sound caused by femoral artery stenosis using short-term Fourier and wavelet transform methods. IEEE Trans Biomed Eng. 1994 Oct; 41(10):921-8.
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Raymond RM, Jandhyala BS, Grega GJ. The interrelationship among bradykinin, various vasoactive substances, and macromolecular permeability in the canine forelimb. Microvasc Res. 1980 May; 19(3):329-37.