Ventral Tegmental Area
"Ventral Tegmental Area" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A region in the MESENCEPHALON which is dorsomedial to the SUBSTANTIA NIGRA and ventral to the RED NUCLEUS. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the NUCLEUS ACCUMBENS. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of SCHIZOPHRENIA.
Descriptor ID |
D017557
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MeSH Number(s) |
A08.186.211.132.659.413.875.820
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Concept/Terms |
Ventral Tegmental Area- Ventral Tegmental Area
- Tegmental Area, Ventral
- Ventral Tegmental Area of Tsai
- Area Tegmentalis Ventralis
- Area Tegmentalis Ventrali
- Tegmentalis Ventrali, Area
- Tegmentalis Ventralis, Area
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Below are MeSH descriptors whose meaning is more general than "Ventral Tegmental Area".
Below are MeSH descriptors whose meaning is more specific than "Ventral Tegmental Area".
This graph shows the total number of publications written about "Ventral Tegmental Area" by people in this website by year, and whether "Ventral Tegmental Area" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1997 | 1 | 0 | 1 | 2000 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2011 | 3 | 0 | 3 | 2014 | 1 | 0 | 1 | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ventral Tegmental Area" by people in Profiles.
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Beier KT, Steinberg EE, DeLoach KE, Xie S, Miyamichi K, Schwarz L, Gao XJ, Kremer EJ, Malenka RC, Luo L. Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping. Cell. 2015 Jul 30; 162(3):622-34.
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Zhang D, Dragomir A, Akay YM, Akay M. Nicotine exposure increases the complexity of dopamine neurons in the parainterfascicular nucleus (PIF) sub-region of VTA. J Neuroeng Rehabil. 2014 Jun 12; 11:103.
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Chen T, Zhang D, Dragomir A, Kobayashi K, Akay Y, Akay M. Investigating the influence of PFC transection and nicotine on dynamics of AMPA and NMDA receptors of VTA dopaminergic neurons. J Neuroeng Rehabil. 2011 Oct 21; 8:58.
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Chen TY, Zhang D, Dragomir A, Akay Y, Akay M. The effects of nicotine exposure and PFC transection on the time-frequency distribution of VTA DA neurons' firing activities. Med Biol Eng Comput. 2011 May; 49(5):605-12.
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Chen TY, Zhang D, Dragomir A, Akay YM, Akay M. Complexity of VTA DA neural activities in response to PFC transection in nicotine treated rats. J Neuroeng Rehabil. 2011 Feb 27; 8:13.
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Chen TY, Dragomir A, Zhang D, Akay Y, Akay M. Prefrontal cortex deletion affects the dopaminergic neural firing complexity in nicotine-treated ventral tegmental area. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:4526-9.
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Haile CN, Hiroi N, Nestler EJ, Kosten TA. Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats. Synapse. 2001 Sep 01; 41(3):179-90.
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Carlezon WA, Haile CN, Coppersmith R, Hayashi Y, Malinow R, Neve RL, Nestler EJ. Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1. J Neurosci. 2000 Mar 01; 20(5):RC62.
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Carlezon WA, Boundy VA, Haile CN, Lane SB, Kalb RG, Neve RL, Nestler EJ. Sensitization to morphine induced by viral-mediated gene transfer. Science. 1997 Aug 08; 277(5327):812-4.
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Ortiz J, DeCaprio JL, Kosten TA, Nestler EJ. Strain-selective effects of corticosterone on locomotor sensitization to cocaine and on levels of tyrosine hydroxylase and glucocorticoid receptor in the ventral tegmental area. Neuroscience. 1995 Jul; 67(2):383-97.
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