 Pseudogenes
"Pseudogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes bearing close resemblance to known genes at different loci, but rendered non-functional by additions or deletions in structure that prevent normal transcription or translation. When lacking introns and containing a poly-A segment near the downstream end (as a result of reverse copying from processed nuclear RNA into double-stranded DNA), they are called processed genes.
| Descriptor ID |
D011544
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| MeSH Number(s) |
G05.360.340.024.340.700
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| Concept/Terms |
beta-Tubulin Pseudogene- beta-Tubulin Pseudogene
- Pseudogene, beta-Tubulin
- Pseudogenes, beta-Tubulin
- beta Tubulin Pseudogene
- beta-Tubulin Pseudogenes
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Below are MeSH descriptors whose meaning is more general than "Pseudogenes".
Below are MeSH descriptors whose meaning is more specific than "Pseudogenes".
This graph shows the total number of publications written about "Pseudogenes" by people in this website by year, and whether "Pseudogenes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pseudogenes" by people in Profiles.
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Woehle C, Kusdian G, Radine C, Graur D, Landan G, Gould SB. The parasite Trichomonas vaginalis expresses thousands of pseudogenes and long non-coding RNAs independently from functional neighbouring genes. BMC Genomics. 2014 Oct 17; 15:906.
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Tirumalai MR, Rastogi R, Zamani N, O'Bryant Williams E, Allen S, Diouf F, Kwende S, Weinstock GM, Venkateswaran KJ, Fox GE. Candidate genes that may be responsible for the unusual resistances exhibited by Bacillus pumilus SAFR-032 spores. PLoS One. 2013; 8(6):e66012.
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Meisel RP. Evolutionary dynamics of recently duplicated genes: Selective constraints on diverging paralogs in the Drosophila pseudoobscura genome. J Mol Evol. 2009 Jul; 69(1):81-93.
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Petrosino JF, Xiang Q, Karpathy SE, Jiang H, Yerrapragada S, Liu Y, Gioia J, Hemphill L, Gonzalez A, Raghavan TM, Uzman A, Fox GE, Highlander S, Reichard M, Morton RJ, Clinkenbeard KD, Weinstock GM. Chromosome rearrangement and diversification of Francisella tularensis revealed by the type B (OSU18) genome sequence. J Bacteriol. 2006 Oct; 188(19):6977-85.
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Mitchell A, Graur D. Inferring the pattern of spontaneous mutation from the pattern of substitution in unitary pseudogenes of Mycobacterium leprae and a comparison of mutation patterns among distantly related organisms. J Mol Evol. 2005 Dec; 61(6):795-803.
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McLeod MP, Qin X, Karpathy SE, Gioia J, Highlander SK, Fox GE, McNeill TZ, Jiang H, Muzny D, Jacob LS, Hawes AC, Sodergren E, Gill R, Hume J, Morgan M, Fan G, Amin AG, Gibbs RA, Hong C, Yu XJ, Walker DH, Weinstock GM. Complete genome sequence of Rickettsia typhi and comparison with sequences of other rickettsiae. J Bacteriol. 2004 Sep; 186(17):5842-55.
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Hazkani-Covo E, Sorek R, Graur D. Evolutionary dynamics of large numts in the human genome: rarity of independent insertions and abundance of post-insertion duplications. J Mol Evol. 2003 Feb; 56(2):169-74.
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Ophir R, Itoh T, Graur D, Gojobori T. A simple method for estimating the intensity of purifying selection in protein-coding genes. Mol Biol Evol. 1999 Jan; 16(1):49-53.
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Ophir R, Graur D. Patterns and rates of indel evolution in processed pseudogenes from humans and murids. Gene. 1997 Dec 31; 205(1-2):191-202.
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Graur D, Shuali Y, Li WH. Deletions in processed pseudogenes accumulate faster in rodents than in humans. J Mol Evol. 1989 Apr; 28(4):279-85.
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