 Sequence Alignment
"Sequence Alignment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
| Descriptor ID |
D016415
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| MeSH Number(s) |
E05.393.751
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| Concept/Terms |
Sequence Alignment- Sequence Alignment
- Alignment, Sequence
- Alignments, Sequence
- Sequence Alignments
Determination, Sequence Homology- Determination, Sequence Homology
- Determinations, Sequence Homology
- Sequence Homology Determinations
- Sequence Homology Determination
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Below are MeSH descriptors whose meaning is more general than "Sequence Alignment".
Below are MeSH descriptors whose meaning is more specific than "Sequence Alignment".
This graph shows the total number of publications written about "Sequence Alignment" by people in this website by year, and whether "Sequence Alignment" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 3 | 3 | | 1999 | 0 | 3 | 3 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 5 | 5 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 2 | 0 | 2 | | 2009 | 0 | 2 | 2 | | 2010 | 2 | 3 | 5 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 3 | 3 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sequence Alignment" by people in Profiles.
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Smith IN, Briggs JM. Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer. Proteins. 2016 Nov; 84(11):1625-1643.
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Menon DU, Coarfa C, Xiao W, Gunaratne PH, Meller VH. siRNAs from an X-linked satellite repeat promote X-chromosome recognition in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16460-5.
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Zufall RA, Sturm M, Mahon BC. Evolution of germline-limited sequences in two populations of the ciliate Chilodonella uncinata. J Mol Evol. 2012 Apr; 74(3-4):140-6.
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Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J. Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production. J Biol Chem. 2012 Apr 06; 287(15):12121-31.
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Dong D, Wu B, Chow D, Hu M. Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling. Drug Metab Rev. 2012 May; 44(2):192-208.
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Gunaratne PH, Lin YC, Benham AL, Drnevich J, Coarfa C, Tennakoon JB, Creighton CJ, Kim JH, Milosavljevic A, Watson M, Griffiths-Jones S, Clayton DF. Song exposure regulates known and novel microRNAs in the zebra finch auditory forebrain. BMC Genomics. 2011 May 31; 12(1):277.
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Gorman MA, Uboldi AD, Walsh PJ, Tan KS, Hansen G, Huyton T, Ji H, Curtis J, Kedzierski L, Papenfuss AT, Dogovski C, Perugini MA, Simpson RJ, Handman E, Parker MW. Crystal structure of the Leishmania major MIX protein: a scaffold protein that mediates protein-protein interactions. Protein Sci. 2011 Jun; 20(6):1060-8.
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Penn O, Privman E, Ashkenazy H, Landan G, Graur D, Pupko T. GUIDANCE: a web server for assessing alignment confidence scores. Nucleic Acids Res. 2010 Jul; 38(Web Server issue):W23-8.
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Meisel RP, Hilldorfer BB, Koch JL, Lockton S, Schaeffer SW. Adaptive evolution of genes duplicated from the Drosophila pseudoobscura neo-X chromosome. Mol Biol Evol. 2010 Aug; 27(8):1963-78.
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Penn O, Privman E, Landan G, Graur D, Pupko T. An alignment confidence score capturing robustness to guide tree uncertainty. Mol Biol Evol. 2010 Aug; 27(8):1759-67.
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