Receptors, Adrenergic
"Receptors, Adrenergic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction.
Descriptor ID |
D011941
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MeSH Number(s) |
D12.776.543.750.069.300.300 D12.776.543.750.100.150.300 D12.776.543.750.720.330.300
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Concept/Terms |
Receptors, Adrenergic- Receptors, Adrenergic
- Receptors, Epinephrine
- Adrenergic Receptors
- Epinephrine Receptors
- Adrenoceptors
- Adrenergic Receptor
- Receptor, Adrenergic
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Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.069]
- Receptors, Catecholamine [D12.776.543.750.069.300]
- Receptors, Adrenergic [D12.776.543.750.069.300.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Catecholamine [D12.776.543.750.100.150]
- Receptors, Adrenergic [D12.776.543.750.100.150.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic".
This graph shows the total number of publications written about "Receptors, Adrenergic" by people in this website by year, and whether "Receptors, Adrenergic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1981 | 1 | 0 | 1 | 1983 | 2 | 0 | 2 | 1986 | 1 | 0 | 1 | 1988 | 1 | 0 | 1 | 1989 | 0 | 1 | 1 | 1991 | 2 | 0 | 2 | 1992 | 1 | 0 | 1 | 1994 | 1 | 0 | 1 | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Adrenergic" by people in Profiles.
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Shivachar AC, Eikenburg DC. Differential effects of epinephrine and norepinephrine on cAMP response and g(i3)alpha protein expression in cultured sympathetic neurons. J Pharmacol Exp Ther. 1999 Oct; 291(1):258-64.
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Hieble JP, Bond RA. New directions in adrenoceptor pharmacology. Trends Pharmacol Sci. 1994 Nov; 15(11):397-9.
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Sadeghi HM, Eikenburg DC. Chronic epinephrine treatment fails to alter prejunctional adrenoceptor modulation of sympathetic neurotransmission in the rat mesentery. J Pharmacol Exp Ther. 1992 Jun; 261(3):924-30.
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Ruck A, Kendall DA, Hill SJ. Alpha- and beta-adrenoceptor regulation of cyclic AMP accumulation in cultured rat astrocytes. A comparison of primary protoplasmic and mixed fibrous/protoplasmic astroglial cultures. Biochem Pharmacol. 1991 Jun 21; 42(1):59-69.
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Lokhandwala MF, Hegde SS. Cardiovascular pharmacology of adrenergic and dopaminergic receptors: therapeutic significance in congestive heart failure. Am J Med. 1991 May 29; 90(5B):2S-9S.
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Schwartz DD, Eikenburg DC. Acute epinephrine treatment fails to facilitate stimulus-induced neurotransmitter overflow in the isolated perfused rat kidney. J Pharmacol Exp Ther. 1989 Apr; 249(1):177-83.
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Bond RA, Clarke DE. Agonist and antagonist characterization of a putative adrenoceptor with distinct pharmacological properties from the alpha- and beta-subtypes. Br J Pharmacol. 1988 Nov; 95(3):723-34.
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Bond RA, Charlton KG, Clarke DE. Evidence for a receptor mediated action of norepinephrine distinct from alpha- and beta-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol. 1986 Nov; 334(3):261-6.
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Ekas RD, Steenberg ML, Woods MS, Lokhandwala MF. Presynaptic alpha- and beta-adrenoceptor stimulation and norepinephrine release in the spontaneously hypertensive rat. Hypertension. 1983 Mar-Apr; 5(2):198-204.
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Augustine SJ, Tachikawa S, Lokhandwala MF, Buckley JP. Central alpha-adrenergic control of blood pressure. Effects of clonidine withdrawal. Chest. 1983 Feb; 83(2 Suppl):328-31.
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