Receptors, Adrenergic, alpha
"Receptors, Adrenergic, alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
Descriptor ID |
D011942
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MeSH Number(s) |
D12.776.543.750.069.300.300.300 D12.776.543.750.100.150.300.300 D12.776.543.750.720.330.300.300
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Concept/Terms |
Receptors, Adrenergic, alpha- Receptors, Adrenergic, alpha
- Receptor, Adrenergic, alpha
- alpha-Adrenergic Receptors
- alpha Adrenergic Receptors
- Receptors, alpha-Adrenergic
- Receptors, alpha Adrenergic
- Adrenergic alpha-Receptors
- Adrenergic alpha Receptors
- alpha-Receptors, Adrenergic
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Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.069]
- Receptors, Catecholamine [D12.776.543.750.069.300]
- Receptors, Adrenergic [D12.776.543.750.069.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.069.300.300.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Catecholamine [D12.776.543.750.100.150]
- Receptors, Adrenergic [D12.776.543.750.100.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.100.150.300.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.330.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha" by people in this website by year, and whether "Receptors, Adrenergic, alpha" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1980 | 0 | 1 | 1 | 1981 | 1 | 0 | 1 | 1983 | 2 | 1 | 3 | 1984 | 1 | 0 | 1 | 1985 | 0 | 1 | 1 | 1986 | 1 | 0 | 1 | 1988 | 1 | 0 | 1 | 1990 | 0 | 1 | 1 | 1993 | 1 | 1 | 2 | 1995 | 0 | 1 | 1 | 1996 | 2 | 0 | 2 | 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Adrenergic, alpha" by people in Profiles.
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Wilborn TW, Sun D, Schafer JA. Expression of multiple alpha-adrenoceptor isoforms in rat CCD. Am J Physiol. 1998 Jul; 275(1 Pt 2):F111-8.
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Haynes JM, Hill SJ. Alpha-adrenoceptor mediated responses of the cauda epididymis of the guinea-pig. Br J Pharmacol. 1996 Nov; 119(6):1203-10.
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Apparsundaram S, Eikenburg DC. Prejunctional alpha adrenoceptor desensitization in rat heart after chronic epinephrine treatment. J Pharmacol Exp Ther. 1996 Aug; 278(2):862-70.
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Apparsundaram S, Eikenburg DC. Role of prejunctional beta adrenoceptors in rat cardiac sympathetic neurotransmission. J Pharmacol Exp Ther. 1995 Feb; 272(2):519-26.
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Gopalakrishnan SM, Chen C, Lokhandwala MF. Identification of alpha 1-adrenoceptor subtypes in rat renal proximal tubules. Eur J Pharmacol. 1993 Dec 21; 250(3):469-72.
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Chen C, Beach RE, Lokhandwala MF. Dopamine fails to inhibit renal tubular sodium pump in hypertensive rats. Hypertension. 1993 Mar; 21(3):364-72.
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Eikenburg DC. Effects of chronic norepinephrine administration on sympathetic neurotransmission in the isolated perfused rat kidney. J Pharmacol Exp Ther. 1990 Dec; 255(3):1053-9.
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Hill SJ, Straw RM. Alpha 2-adrenoceptor-mediated inhibition of histamine release from rat cerebral cortical slices. Br J Pharmacol. 1988 Dec; 95(4):1213-9.
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Hamed AT, Jandhyala BS, Lokhandwala MF. Evaluation of the role of alpha-1 and alpha-2 adrenoceptors in the maintenance of neurogenic tone to the hindlimb vasculature. J Pharmacol Exp Ther. 1986 Aug; 238(2):599-605.
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Jandhyala BS. Studies on the effects of felodipine on the vascular resistance and reactivity in pentobarbital anesthetized dogs. Naunyn Schmiedebergs Arch Pharmacol. 1985 Jun; 329(4):398-403.
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