 Retinaldehyde
"Retinaldehyde" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration.
| Descriptor ID |
D012172
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| MeSH Number(s) |
D02.047.850 D02.455.326.271.665.202.495.690 D02.455.426.392.368.367.379.249.700.690 D02.455.849.131.495.690 D23.767.261.700.690
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| Concept/Terms |
Retinaldehyde- Retinaldehyde
- Vitamin A Aldehyde
- Aldehyde, Vitamin A
- Retinene
- Axerophthal
- Retinal
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Below are MeSH descriptors whose meaning is more general than "Retinaldehyde".
Below are MeSH descriptors whose meaning is more specific than "Retinaldehyde".
This graph shows the total number of publications written about "Retinaldehyde" by people in this website by year, and whether "Retinaldehyde" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinaldehyde" by people in Profiles.
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Kanan Y, Gordon WC, Mukherjee PK, Bazan NG, Al-Ubaidi MR. Neuroprotectin D1 is synthesized in the cone photoreceptor cell line 661W and elicits protection against light-induced stress. Cell Mol Neurobiol. 2015 Mar; 35(2):197-204.
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Conley SM, Cai X, Makkia R, Wu Y, Sparrow JR, Naash MI. Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy. Biochim Biophys Acta. 2012 Jul; 1822(7):1169-79.
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Pan Y, Martinez-De Luna RI, Lou CH, Nekkalapudi S, Kelly LE, Sater AK, El-Hodiri HM. Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product. Dev Biol. 2010 Mar 15; 339(2):494-506.
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Kanan Y, Kasus-Jacobi A, Moiseyev G, Sawyer K, Ma JX, Al-Ubaidi MR. Retinoid processing in cone and Müller cell lines. Exp Eye Res. 2008 Feb; 86(2):344-54.
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Kanan Y, Moiseyev G, Agarwal N, Ma JX, Al-Ubaidi MR. Light induces programmed cell death by activating multiple independent proteases in a cone photoreceptor cell line. Invest Ophthalmol Vis Sci. 2007 Jan; 48(1):40-51.
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Fu Y, Zhong H, Wang MH, Luo DG, Liao HW, Maeda H, Hattar S, Frishman LJ, Yau KW. Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin. Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10339-44.
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Tan E, Wang Q, Quiambao AB, Xu X, Qtaishat NM, Peachey NS, Lem J, Fliesler SJ, Pepperberg DR, Naash MI, Al-Ubaidi MR. The relationship between opsin overexpression and photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2001 Mar; 42(3):589-600.
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