 Rhodopsin
"Rhodopsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purplish-red, light-sensitive pigment found in RETINAL ROD CELLS of most vertebrates. It is a complex consisting of a molecule of ROD OPSIN and a molecule of 11-cis retinal (RETINALDEHYDE). Rhodopsin exhibits peak absorption wavelength at about 500 nm.
| Descriptor ID |
D012243
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| MeSH Number(s) |
D12.776.543.750.100.955 D23.767.930.750.500.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rhodopsin".
Below are MeSH descriptors whose meaning is more specific than "Rhodopsin".
This graph shows the total number of publications written about "Rhodopsin" by people in this website by year, and whether "Rhodopsin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 1 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 1 | 2 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 3 | 0 | 3 | | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Rhodopsin" by people in Profiles.
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Chakraborty D, Conley SM, Pittler SJ, Naash MI. Role of RDS and Rhodopsin in Cngb1-Related Retinal Degeneration. Invest Ophthalmol Vis Sci. 2016 Mar; 57(3):787-97.
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Conley SM, Whalen P, Lewin AS, Naash MI. Characterization of Ribozymes Targeting a Congenital Night Blindness Mutation in Rhodopsin Mutation. Adv Exp Med Biol. 2016; 854:509-15.
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Orhan E, Dalkara D, Neuillé M, Lechauve C, Michiels C, Picaud S, Léveillard T, Sahel JA, Naash MI, Lavail MM, Zeitz C, Audo I. Genotypic and phenotypic characterization of P23H line 1 rat model. PLoS One. 2015; 10(5):e0127319.
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Han Z, Banworth MJ, Makkia R, Conley SM, Al-Ubaidi MR, Cooper MJ, Naash MI. Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype. FASEB J. 2015 Jun; 29(6):2535-44.
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Murray AR, Vuong L, Brobst D, Fliesler SJ, Peachey NS, Gorbatyuk MS, Naash MI, Al-Ubaidi MR. Glycosylation of rhodopsin is necessary for its stability and incorporation into photoreceptor outer segment discs. Hum Mol Genet. 2015 May 15; 24(10):2709-23.
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Chakraborty D, Conley SM, Al-Ubaidi MR, Naash MI. Initiation of rod outer segment disc formation requires RDS. PLoS One. 2014; 9(6):e98939.
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Pan Y, Martinez-De Luna RI, Lou CH, Nekkalapudi S, Kelly LE, Sater AK, El-Hodiri HM. Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product. Dev Biol. 2010 Mar 15; 339(2):494-506.
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Murray AR, Fliesler SJ, Al-Ubaidi MR. Rhodopsin: the functional significance of asn-linked glycosylation and other post-translational modifications. Ophthalmic Genet. 2009 Sep; 30(3):109-20.
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Wen XH, Shen L, Brush RS, Michaud N, Al-Ubaidi MR, Gurevich VV, Hamm HE, Lem J, Dibenedetto E, Anderson RE, Makino CL. Overexpression of rhodopsin alters the structure and photoresponse of rod photoreceptors. Biophys J. 2009 Feb; 96(3):939-50.
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Chakraborty D, Ding XQ, Fliesler SJ, Naash MI. Outer segment oligomerization of Rds: evidence from mouse models and subcellular fractionation. Biochemistry. 2008 Jan 29; 47(4):1144-56.
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