 Tacrine
"Tacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
| Descriptor ID |
D013619
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| MeSH Number(s) |
D03.494.046.250.900
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| Concept/Terms |
Tacrine- Tacrine
- 1,2,3,4-Tetrahydroaminoacridine
- Tetrahydroaminoacridine
- 1,2,3,4-Tetrahydro-9-acridinamine
- 9-Amino-1,2,3,4-Tetrahydroacridine
THA- THA
- Woods Brand of Tacrine Hydrochloride
Cognex- Cognex
- OTL Pharm Brand of Tacrine Hydrochloride
- Parke Davis Brand of Tacrine Hydrochloride
- Horizon Brand of Tacrine Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Tacrine".
Below are MeSH descriptors whose meaning is more specific than "Tacrine".
This graph shows the total number of publications written about "Tacrine" by people in this website by year, and whether "Tacrine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tacrine" by people in Profiles.
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Doody RS, Dunn JK, Clark CM, Farlow M, Foster NL, Liao T, Gonzales N, Lai E, Massman P. Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Jul-Aug; 12(4):295-300.
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Wlodek ST, Antosiewicz J, McCammon JA, Straatsma TP, Gilson MK, Briggs JM, Humblet C, Sussman JL. Binding of tacrine and 6-chlorotacrine by acetylcholinesterase. Biopolymers. 1996 Jan; 38(1):109-17.
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