 Second Messenger Systems
"Second Messenger Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.
| Descriptor ID |
D015290
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| MeSH Number(s) |
G02.111.087.800.800 G02.149.115.800.800 G04.299.880.800
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| Concept/Terms |
Second Messenger Systems- Second Messenger Systems
- Second Messenger System
- System, Second Messenger
- Systems, Second Messenger
- Intracellular Second Messengers
- Intracellular Second Messenger
- Messengers, Intracellular Second
- Second Messenger, Intracellular
- Second Messengers, Intracellular
Second Messengers- Second Messengers
- Messenger, Second
- Messengers, Second
- Second Messenger
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Below are MeSH descriptors whose meaning is more general than "Second Messenger Systems".
Below are MeSH descriptors whose meaning is more specific than "Second Messenger Systems".
This graph shows the total number of publications written about "Second Messenger Systems" by people in this website by year, and whether "Second Messenger Systems" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 1 | 1 | | 1991 | 2 | 0 | 2 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Second Messenger Systems" by people in Profiles.
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Bouron A, Chauvet S, Dryer S, Rosado JA. Second Messenger-Operated Calcium Entry Through TRPC6. Adv Exp Med Biol. 2016; 898:201-49.
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Storer Samaniego C, Suh JH, Chattopadhyay A, Olivares K, Guy N, Sivils JC, Dey P, Yumoto F, Fletterick RJ, Strom AM, Gustafsson JÅ, Webb P, Cox MB. The FKBP52 Cochaperone Acts in Synergy with ß-Catenin to Potentiate Androgen Receptor Signaling. PLoS One. 2015; 10(7):e0134015.
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Trivedi M, Narkar VA, Hussain T, Lokhandwala MF. Dopamine recruits D1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F921-31.
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Baker JG, Hall IP, Hill SJ. Influence of agonist efficacy and receptor phosphorylation on antagonist affinity measurements: differences between second messenger and reporter gene responses. Mol Pharmacol. 2003 Sep; 64(3):679-88.
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Hussain T, Lokhandwala MF. Renal dopamine receptors and hypertension. Exp Biol Med (Maywood). 2003 Feb; 228(2):134-42.
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Cordeaux Y, Hill SJ. Mechanisms of cross-talk between G-protein-coupled receptors. Neurosignals. 2002 Jan-Feb; 11(1):45-57.
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Dickenson JM, Hill SJ. Human 5-HT1B receptor stimulated inositol phospholipid hydrolysis in CHO cells: synergy with Gq-coupled receptors. Eur J Pharmacol. 1998 May 08; 348(2-3):279-85.
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Tsang YT, Neelamegham S, Hu Y, Berg EL, Burns AR, Smith CW, Simon SI. Synergy between L-selectin signaling and chemotactic activation during neutrophil adhesion and transmigration. J Immunol. 1997 Nov 01; 159(9):4566-77.
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D'Souza T, Dryer SE. Intracellular free Ca2+ in dissociated cells of the chick pineal gland: regulation by membrane depolarization, second messengers and neuromodulators, and evidence for release of intracellular Ca2+ stores. Brain Res. 1994 Sep 05; 656(1):85-94.
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Dickenson JM, Hill SJ. Coupling of histamine H1 and adenosine A1 receptors to phospholipase C in DDT1MF-2 cells: synergistic interactions and regulation by cyclic AMP. Biochem Soc Trans. 1993 Nov; 21(4):1124-9.
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