 Guanosine 5'-O-(3-Thiotriphosphate)
"Guanosine 5'-O-(3-Thiotriphosphate)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
| Descriptor ID |
D016244
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| MeSH Number(s) |
D02.886.765.380 D13.695.667.454.504.380 D13.695.827.426.504.380 D13.695.900.380
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| Concept/Terms |
Guanosine 5'-O-(3-Thiotriphosphate)- Guanosine 5'-O-(3-Thiotriphosphate)
- GTP gamma S
- gamma S, GTP
- GTPgammaS
- Guanosine 5'-(gamma-S)Triphosphate
- gamma-Thio-GTP
- gamma Thio GTP
- Guanosine 5'-(3-O-Thio)Triphosphate
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Below are MeSH descriptors whose meaning is more general than "Guanosine 5'-O-(3-Thiotriphosphate)".
Below are MeSH descriptors whose meaning is more specific than "Guanosine 5'-O-(3-Thiotriphosphate)".
This graph shows the total number of publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in this website by year, and whether "Guanosine 5'-O-(3-Thiotriphosphate)" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1992 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 4 | 4 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in Profiles.
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George LE, Lokhandwala MF, Asghar M. Novel role of NF-?B-p65 in antioxidant homeostasis in human kidney-2 cells. Am J Physiol Renal Physiol. 2012 Jun 01; 302(11):F1440-6.
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George L, Lokhandwala MF, Asghar M. Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1174-80.
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Asghar M, Chillar A, Lokhandwala MF. Renal proximal tubules from old Fischer 344 rats grow into epithelial cells in cultures and exhibit increased oxidative stress and reduced D1 receptor function. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1326-31.
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Banday AA, Lokhandwala MF. Oxidative stress reduces renal dopamine D1 receptor-Gq/11alpha G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F306-15.
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Banday AA, Fazili FR, Marwaha A, Lokhandwala MF. Mitogen-activated protein kinase upregulation reduces renal D1 receptor affinity and G-protein coupling in obese rats. Kidney Int. 2007 Mar; 71(5):397-406.
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Asghar M, Banday AA, Fardoun RZ, Lokhandwala MF. Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2. Free Radic Biol Med. 2006 Jan 01; 40(1):13-20.
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Trivedi M, Narkar VA, Hussain T, Lokhandwala MF. Dopamine recruits D1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F921-31.
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Marwaha A, Banday AA, Lokhandwala MF. Reduced renal dopamine D1 receptor function in streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol. 2004 Mar; 286(3):F451-7.
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Banday AA, Asghar M, Hussain T, Lokhandwala MF. Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin. Hypertension. 2003 Jun; 41(6):1353-8.
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Cordeaux Y, Briddon SJ, Megson AE, McDonnell J, Dickenson JM, Hill SJ. Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A(1) receptor: evidence for signaling pathway-dependent changes in agonist potency and relative intrinsic activity. Mol Pharmacol. 2000 Nov; 58(5):1075-84.
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