Photosensitizing Agents
"Photosensitizing Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.
Descriptor ID |
D017319
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MeSH Number(s) |
D27.505.954.444.600 D27.505.954.600.710
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Concept/Terms |
Photosensitizing Effect- Photosensitizing Effect
- Effect, Photosensitizing
- Photosensitizing Effects
- Effects, Photosensitizing
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Below are MeSH descriptors whose meaning is more general than "Photosensitizing Agents".
Below are MeSH descriptors whose meaning is more specific than "Photosensitizing Agents".
This graph shows the total number of publications written about "Photosensitizing Agents" by people in this website by year, and whether "Photosensitizing Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2012 | 1 | 1 | 2 | 2013 | 2 | 0 | 2 | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Photosensitizing Agents" by people in Profiles.
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Singh M, Li J, Han Z, Vantipalli S, Liu CH, Wu C, Raghunathan R, Aglyamov SR, Twa MD, Larin KV. Evaluating the Effects of Riboflavin/UV-A and Rose-Bengal/Green Light Cross-Linking of the Rabbit Cornea by Noncontact Optical Coherence Elastography. Invest Ophthalmol Vis Sci. 2016 Jul 01; 57(9):OCT112-20.
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Lincoln R, Kohler L, Monro S, Yin H, Stephenson M, Zong R, Chouai A, Dorsey C, Hennigar R, Thummel RP, McFarland SA. Exploitation of long-lived 3IL excited states for metal-organic photodynamic therapy: verification in a metastatic melanoma model. J Am Chem Soc. 2013 Nov 13; 135(45):17161-75.
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Ethirajan M, Chen P, Ohulchanskyy TY, Goswami LN, Gupta A, Srivatsan A, Dobhal MP, Missert JR, Prasad PN, Kadish KM, Pandey RK. Regioselective synthesis and photophysical and electrochemical studies of 20-substituted cyanine dye-purpurinimide conjugates: incorporation of Ni(II) into the conjugate enhances its tumor-uptake and fluorescence-imaging ability. Chemistry. 2013 May 17; 19(21):6670-84.
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Sears RB, Joyce LE, Ojaimi M, Gallucci JC, Thummel RP, Turro C. Photoinduced ligand exchange and DNA binding of cis-[Ru(phpy)(phen)(CH3CN)2]+ with long wavelength visible light. J Inorg Biochem. 2013 Apr; 121:77-87.
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Kozyrev A, Ethirajan M, Chen P, Ohkubo K, Robinson BC, Barkigia KM, Fukuzumi S, Kadish KM, Pandey RK. Synthesis, photophysical and electrochemistry of near-IR absorbing bacteriochlorins related to bacteriochlorophyll a. J Org Chem. 2012 Nov 16; 77(22):10260-71.
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Williams MP, Ethirajan M, Ohkubo K, Chen P, Pera P, Morgan J, White WH, Shibata M, Fukuzumi S, Kadish KM, Pandey RK. Synthesis, photophysical, electrochemical, tumor-imaging, and phototherapeutic properties of purpurinimide-N-substituted cyanine dyes joined with variable lengths of linkers. Bioconjug Chem. 2011 Nov 16; 22(11):2283-95.
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Lee J, Udugamasooriya DG, Lim HS, Kodadek T. Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. Nat Chem Biol. 2010 Apr; 6(4):258-60.
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Liu Y, Hammitt R, Lutterman DA, Joyce LE, Thummel RP, Turro C. Ru(II) complexes of new tridentate ligands: unexpected high yield of sensitized 1O2. Inorg Chem. 2009 Jan 05; 48(1):375-85.
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Chen Y, Ohkubo K, Zhang M, Wenbo E, Liu W, Pandey SK, Ciesielski M, Baumann H, Erin T, Fukuzumi S, Kadish KM, Fenstermaker R, Oseroff A, Pandey RK. Photophysical, electrochemical characteristics and cross-linking of STAT-3 protein by an efficient bifunctional agent for fluorescence image-guided photodynamic therapy. Photochem Photobiol Sci. 2007 Dec; 6(12):1257-67.
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