 Gene Deletion
"Gene Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
| Descriptor ID |
D017353
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| MeSH Number(s) |
G05.355.600.800.320 G05.365.590.762.320
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| Concept/Terms |
Gene Deletion- Gene Deletion
- Deletion, Gene
- Deletions, Gene
- Gene Deletions
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Below are MeSH descriptors whose meaning is more general than "Gene Deletion".
Below are MeSH descriptors whose meaning is more specific than "Gene Deletion".
This graph shows the total number of publications written about "Gene Deletion" by people in this website by year, and whether "Gene Deletion" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1995 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1999 | 2 | 1 | 3 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 2 | 1 | 3 | | 2008 | 2 | 2 | 4 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 3 | 3 | | 2014 | 2 | 1 | 3 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Deletion" by people in Profiles.
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Tan X, Banerjee P, Guo HF, Ireland S, Pankova D, Ahn YH, Nikolaidis IM, Liu X, Zhao Y, Xue Y, Burns AR, Roybal J, Gibbons DL, Zal T, Creighton CJ, Ungar D, Wang Y, Kurie JM. Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11. J Clin Invest. 2017 Jan 03; 127(1):117-131.
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Xia M, Abais JM, Koka S, Meng N, Gehr TW, Boini KM, Li PL. Characterization and Activation of NLRP3 Inflammasomes in the Renal Medulla in Mice. Kidney Blood Press Res. 2016; 41(2):208-21.
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Lam FW, Phillips J, Landry P, Magadi S, Smith CW, Rumbaut RE, Burns AR. Platelet recruitment promotes keratocyte repopulation following corneal epithelial abrasion in the mouse. PLoS One. 2015; 10(3):e0118950.
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Xia M, Conley SM, Li G, Li PL, Boini KM. Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion. Cell Physiol Biochem. 2014; 34(3):829-41.
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Boini KM, Xia M, Abais JM, Li G, Pitzer AL, Gehr TW, Zhang Y, Li PL. Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing. Biochim Biophys Acta. 2014 May; 1843(5):836-45.
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Li X, Xu M, Pitzer AL, Xia M, Boini KM, Li PL, Zhang Y. Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis. J Mol Med (Berl). 2014 May; 92(5):473-85.
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Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X. Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects. Dev Biol. 2013 Nov 15; 383(2):239-52.
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Guillory AN, Yin X, Wijaya CS, Diaz Diaz AC, Rababa'h A, Singh S, Atrooz F, Sadayappan S, McConnell BK. Enhanced cardiac function in Gravin mutant mice involves alterations in the ß-adrenergic receptor signaling cascade. PLoS One. 2013; 8(9):e74784.
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Koirala A, Conley SM, Makkia R, Liu Z, Cooper MJ, Sparrow JR, Naash MI. Persistence of non-viral vector mediated RPE65 expression: case for viability as a gene transfer therapy for RPE-based diseases. J Control Release. 2013 Dec 28; 172(3):745-52.
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Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J. Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012; 7(2):e31005.
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