 Self Tolerance
"Self Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.
| Descriptor ID |
D017634
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| MeSH Number(s) |
G12.425.746.425.800
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| Concept/Terms |
Self Tolerance- Self Tolerance
- Self Tolerances
- Tolerance, Self
- Tolerances, Self
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Below are MeSH descriptors whose meaning is more general than "Self Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Self Tolerance".
This graph shows the total number of publications written about "Self Tolerance" by people in this website by year, and whether "Self Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 |
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Below are the most recent publications written about "Self Tolerance" by people in Profiles.
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Ladi E, Schwickert TA, Chtanova T, Chen Y, Herzmark P, Yin X, Aaron H, Chan SW, Lipp M, Roysam B, Robey EA. Thymocyte-dendritic cell interactions near sources of CCR7 ligands in the thymic cortex. J Immunol. 2008 Nov 15; 181(10):7014-23.
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Sayed BA, Christy A, Quirion MR, Brown MA. The master switch: the role of mast cells in autoimmunity and tolerance. Annu Rev Immunol. 2008; 26:705-39.
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Christy AL, Brown MA. The multitasking mast cell: positive and negative roles in the progression of autoimmunity. J Immunol. 2007 Sep 01; 179(5):2673-9.
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