Encephalomyelitis, Autoimmune, Experimental
"Encephalomyelitis, Autoimmune, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
Descriptor ID |
D004681
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MeSH Number(s) |
C10.114.703.300 C10.228.140.695.562.250 C10.314.350.250 C20.111.258.625.300 E05.598.500.500.500
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Concept/Terms |
Encephalomyelitis, Autoimmune, Experimental- Encephalomyelitis, Autoimmune, Experimental
- Allergic Encephalomyelitis, Experimental
- Encephalomyelitis, Experimental Allergic
- Experimental Allergic Encephalomyelitides
- Autoimmune Encephalomyelitis, Experimental
- Experimental Autoimmune Encephalomyelitis
- Encephalomyelitis, Allergic
- Encephalomyelitis, Experimental Autoimmune
- Experimental Allergic Encephalomyelitis
- Allergic Encephalomyelitis
- Autoimmune Experimental Encephalomyelitis
- Encephalomyelitis, Autoimmune Experimental
- Experimental Encephalomyelitis, Autoimmune
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Below are MeSH descriptors whose meaning is more general than "Encephalomyelitis, Autoimmune, Experimental".
- Diseases [C]
- Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
- Nervous System Autoimmune Disease, Experimental [C10.114.703]
- Encephalomyelitis, Autoimmune, Experimental [C10.114.703.300]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Leukoencephalopathies [C10.228.140.695]
- Demyelinating Autoimmune Diseases, CNS [C10.228.140.695.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.140.695.562.250]
- Demyelinating Diseases [C10.314]
- Demyelinating Autoimmune Diseases, CNS [C10.314.350]
- Encephalomyelitis, Autoimmune, Experimental [C10.314.350.250]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Autoimmune Diseases of the Nervous System [C20.111.258]
- Nervous System Autoimmune Disease, Experimental [C20.111.258.625]
- Encephalomyelitis, Autoimmune, Experimental [C20.111.258.625.300]
- Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
- Investigative Techniques [E05]
- Models, Animal [E05.598]
- Disease Models, Animal [E05.598.500]
- Nervous System Autoimmune Disease, Experimental [E05.598.500.500]
- Encephalomyelitis, Autoimmune, Experimental [E05.598.500.500.500]
Below are MeSH descriptors whose meaning is more specific than "Encephalomyelitis, Autoimmune, Experimental".
This graph shows the total number of publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in this website by year, and whether "Encephalomyelitis, Autoimmune, Experimental" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2010 | 1 | 1 | 2 | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Profiles.
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Christy AL, Walker ME, Hessner MJ, Brown MA. Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE. J Autoimmun. 2013 May; 42:50-61.
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Qin X, Guo BT, Wan B, Fang L, Lu L, Wu L, Zang YQ, Zhang JZ. Regulation of Th1 and Th17 cell differentiation and amelioration of experimental autoimmune encephalomyelitis by natural product compound berberine. J Immunol. 2010 Aug 01; 185(3):1855-63.
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Sayed BA, Christy AL, Walker ME, Brown MA. Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment? J Immunol. 2010 Jun 15; 184(12):6891-900.
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Gocke AR, Udugamasooriya DG, Archer CT, Lee J, Kodadek T. Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chem Biol. 2009 Nov 25; 16(11):1133-9.
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Brown MA, Sayed BA, Christy A. Mast cells and the adaptive immune response. J Clin Immunol. 2008 Nov; 28(6):671-6.
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