 Interleukin-12
"Interleukin-12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.
| Descriptor ID |
D018664
|
| MeSH Number(s) |
D12.644.276.374.465.512 D12.776.467.374.465.512 D23.529.374.465.512
|
| Concept/Terms |
Interleukin-12- Interleukin-12
- Edodekin Alfa
- IL 12
- Natural Killer Cell Stimulatory Factor
- IL-12 p70
- IL12
- Interleukin 12
- Interleukin-12 p70
- Interleukin 12 p70
- p70, Interleukin-12
- Cytotoxic Lymphocyte Maturation Factor
- IL-12
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-12".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-12".
This graph shows the total number of publications written about "Interleukin-12" by people in this website by year, and whether "Interleukin-12" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-12" by people in Profiles.
-
Gorla SK, McNair NN, Yang G, Gao S, Hu M, Jala VR, Haribabu B, Striepen B, Cuny GD, Mead JR, Hedstrom L. Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis. Antimicrob Agents Chemother. 2014; 58(3):1603-14.
-
Satwani P, Ayello J, Ven C, O'Neill AF, Simpson LL, Baxi L, Cairo MS. Immaturity of IL-18 gene expression and protein production in cord blood (CB) versus peripheral blood (PB) mononuclear cells and differential effects in natural killer (NK) cell development and function. Br J Haematol. 2005 Jul; 130(2):284-92.
-
Elso C, Toohey B, Reid GE, Poetter K, Simpson RJ, Foote SJ. Mutation detection using mass spectrometric separation of tiny oligonucleotide fragments. Genome Res. 2002 Sep; 12(9):1428-33.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|