Xanthine
"Xanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)
Descriptor ID |
D019820
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MeSH Number(s) |
D03.132.960.938 D03.438.759.758.824.938
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Xanthine".
Below are MeSH descriptors whose meaning is more specific than "Xanthine".
This graph shows the total number of publications written about "Xanthine" by people in this website by year, and whether "Xanthine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1992 | 0 | 1 | 1 | 1994 | 0 | 2 | 2 | 1995 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Xanthine" by people in Profiles.
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Webb A, Bond R, McLean P, Uppal R, Benjamin N, Ahluwalia A. Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13683-8.
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Jacinto SM, Chintala MS, Lokhandwala MF, Jandhyala BS. Efficacy and mechanisms of dopexamine in the prevention of ischemia-reperfusion induced organ damage: role of oxygen free radicals. Clin Exp Hypertens. 1997 Jan-Feb; 19(1-2):181-90.
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Jacinto SM, Lokhandwala MF, Jandhyala BS. Effect of pharmacological interventions in the prevention of lipid peroxidation and respiratory depression induced by oxygen free radicals in anesthetized rats. Free Radic Biol Med. 1996; 21(6):791-9.
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Hoffenberg S, Nikolova L, Pan JY, Daniel DS, Wessling-Resnick M, Knoll BJ, Dickey BF. Functional and structural interactions of the Rab5 D136N mutant with xanthine nucleotides. Biochem Biophys Res Commun. 1995 Oct 04; 215(1):241-9.
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Jacinto SM, Jandhyala BS. Depression of myocardial contractility is not a causative factor for circulatory deterioration in two experimental models of shock in anesthetized dogs. Ann N Y Acad Sci. 1994 Jun 17; 723:345-8.
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Jacinto SM, Jandhyala BS. Salutary effects of dopexamine, a DA-1 and beta-2 agonist, on free radical-induced toxicity in anesthetized rats. Ann N Y Acad Sci. 1994 Jun 17; 723:349-52.
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Jacinto SM, Jandhyala BS. Evaluation of the effects of felodipine, verapamil and hydralazine on the survival rate of rats subjected to lethal effects of oxygen free radicals. Naunyn Schmiedebergs Arch Pharmacol. 1992 Oct; 346(4):457-61.
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