Theophylline
"Theophylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
Descriptor ID |
D013806
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MeSH Number(s) |
D03.132.960.751 D03.438.759.758.824.751
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Concept/Terms |
Theophylline- Theophylline
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 1,3-Dimethylxanthine
- 1,3 Dimethylxanthine
Aerobin- Aerobin
- Fameasan Brand of Theophylline Sodium Glycinate
Bronchoparat- Bronchoparat
- Fujisawa Brand of Theophylline Sodium Glycinate
theo von ct- theo von ct
- ct, theo von
- von ct, theo
- ct-Arzneimittel Brand of Theophylline Sodium Glycinate
- ct Arzneimittel Brand of Theophylline Sodium Glycinate
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Below are MeSH descriptors whose meaning is more general than "Theophylline".
Below are MeSH descriptors whose meaning is more specific than "Theophylline".
This graph shows the total number of publications written about "Theophylline" by people in this website by year, and whether "Theophylline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1981 | 0 | 2 | 2 | 1984 | 0 | 1 | 1 | 1988 | 0 | 1 | 1 | 1989 | 1 | 0 | 1 | 1990 | 0 | 1 | 1 | 1995 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Theophylline" by people in Profiles.
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Ghassabian S, Murray M. Simultaneous in vivo phenotyping of CYP enzymes. Methods Mol Biol. 2013; 987:261-7.
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Cooper JA, Hill SJ, Alexander SP, Rubin PC, Horn EH. Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets. Br J Clin Pharmacol. 1995 Jul; 40(1):43-50.
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Hall IP, Donaldson J, Hill SJ. Modulation of carbachol-induced inositol phosphate formation in bovine tracheal smooth muscle by cyclic AMP phosphodiesterase inhibitors. Biochem Pharmacol. 1990 Apr 15; 39(8):1357-63.
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Hall IP, Hill SJ. Inhibition by salbutamol, forskolin and IBMX of AlF4-induced inositol phosphate formation in bovine airway smooth muscle. Br J Pharmacol. 1989 Dec; 98 Suppl:788P.
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Hegde SS, Lokhandwala MF. Involvement of cyclic-AMP in the hypotensive response to fenoldopam but not to quinpirole in the anaesthetized rat. J Auton Pharmacol. 1988 Mar; 8(1):63-8.
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Alkadhi KA, Brown TR, Sabouni MH. Inhibitory effect of adenosine on transmission in sympathetic ganglia. Naunyn Schmiedebergs Arch Pharmacol. 1984 Nov; 328(1):16-9.
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Ekas RD, Steenberg ML, Eikenburg DC, Lokhandwala MF. Presynaptic inhibition of sympathetic neurotransmission by adenosine in the rat kidney. Eur J Pharmacol. 1981 Dec 17; 76(4):301-7.
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Hom GJ, Lokhandwala MF. Effect of dipyridamole on sympathetic nerve function: role of adenosine and presynaptic purinergic receptors. J Cardiovasc Pharmacol. 1981 Mar-Apr; 3(2):391-401.
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Lokhandwala MF. Inhibition of cardiac sympathetic neurotransmission by adenosine. Eur J Pharmacol. 1979 Dec 20; 60(4):353-7.
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McGuire J, Moellmann G, McKeon F. Cytochalasin B and pigment granule translocation. Cytochalasin B reverses and prevents pigment granule dispersion caused by dibutyryl cyclic AMP and theophylline in Rana pipiens Melanocytes. J Cell Biol. 1972 Mar; 52(3):754-8.
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