 Adenomatous Polyposis Coli Protein
"Adenomatous Polyposis Coli Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.
| Descriptor ID |
D025601
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| MeSH Number(s) |
D05.500.117.249 D12.776.220.040 D12.776.476.081.249 D12.776.624.776.049
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli Protein".
Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli Protein".
This graph shows the total number of publications written about "Adenomatous Polyposis Coli Protein" by people in this website by year, and whether "Adenomatous Polyposis Coli Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Adenomatous Polyposis Coli Protein" by people in Profiles.
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Donehower LA, Creighton CJ, Schultz N, Shinbrot E, Chang K, Gunaratne PH, Muzny D, Sander C, Hamilton SR, Gibbs RA, Wheeler D. MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes. J Pathol. 2013 Jan; 229(1):99-110.
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Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ. Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Electrophoresis. 2012 Jul; 33(12):1873-80.
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Layton MJ, Faux MC, Church NL, Catimel B, Kershaw NJ, Kapp EA, Nowell C, Coates JL, Burgess AW, Simpson RJ. Identification of a Wnt-induced protein complex by affinity proteomics using an antibody that recognizes a sub-population of ß-catenin. Biochim Biophys Acta. 2012 Jul; 1824(7):925-37.
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Rotte A, Bhandaru M, Föller M, Biswas R, Mack AF, Friedrich B, Rexhepaj R, Nasir O, Ackermann TF, Boini KM, Kunzelmann K, Behrens J, Lang F. APC sensitive gastric acid secretion. Cell Physiol Biochem. 2009; 23(1-3):133-42.
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Faux MC, Ross JL, Meeker C, Johns T, Ji H, Simpson RJ, Layton MJ, Burgess AW. Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion. J Cell Sci. 2004 Jan 26; 117(Pt 3):427-39.
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