Retinoblastoma Protein
"Retinoblastoma Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
Descriptor ID |
D016160
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MeSH Number(s) |
D12.776.260.704 D12.776.624.776.745 D12.776.660.807 D12.776.744.770
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Concept/Terms |
p105-Rb Protein- p105-Rb Protein
- p105 Rb Protein
- Retinoblastoma Nuclear Phosphoprotein p105-Rb
- Retinoblastoma Nuclear Phosphoprotein p105 Rb
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Below are MeSH descriptors whose meaning is more general than "Retinoblastoma Protein".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma Protein".
This graph shows the total number of publications written about "Retinoblastoma Protein" by people in this website by year, and whether "Retinoblastoma Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinoblastoma Protein" by people in Profiles.
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Vuong L, Conley SM, Al-Ubaidi MR. Expression and role of p53 in the retina. Invest Ophthalmol Vis Sci. 2012 Mar 15; 53(3):1362-71.
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Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Mol Cell Biol. 2010 Apr; 30(8):1866-77.
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Byrne A, McLaren RP, Mason P, Chai L, Dufault MR, Huang Y, Liang B, Gans JD, Zhang M, Carter K, Gladysheva TB, Teicher BA, Biemann HP, Booker M, Goldberg MA, Klinger KW, Lillie J, Madden SL, Jiang Y. Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence. Exp Cell Res. 2010 Jan 15; 316(2):258-71.
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Chakravarthy MV, Fiorotto ML, Schwartz RJ, Booth FW. Long-term insulin-like growth factor-I expression in skeletal muscles attenuates the enhanced in vitro proliferation ability of the resident satellite cells in transgenic mice. Mech Ageing Dev. 2001 Sep; 122(12):1303-20.
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