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Garret Etgen

TitleProfessor
InstitutionUniversity of Houston
DepartmentMathematics
Address4800 Calhoun Rd
Houston TX 77004
Phone713-743-3510
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Glaesner W, Vick AM, Millican R, Ellis B, Tschang SH, Tian Y, Bokvist K, Brenner M, Koester A, Porksen N, Etgen G, Bumol T. Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein. Diabetes Metab Res Rev. 2010 May; 26(4):287-96. PMID: 20503261.
      View in: PubMed
    2. Shi Q, Canada EJ, Xu Y, Warshawsky AM, Etgen GJ, Broderick CL, Clutinger CK, Irwin LA, Laurila ME, Montrose-Rafizadeh C, Oldham BA, Wang M, Winneroski LL, Xie C, York JS, Yumibe NP, Zink RW, Mantlo N. Design and synthesis of novel and potent amide linked PPARgamma/delta dual agonists. Bioorg Med Chem Lett. 2007 Dec 15; 17(24):6744-9. PMID: 18029178.
      View in: PubMed
    3. Kharitonenkov A, Wroblewski VJ, Koester A, Chen YF, Clutinger CK, Tigno XT, Hansen BC, Shanafelt AB, Etgen GJ. The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21. Endocrinology. 2007 Feb; 148(2):774-81. PMID: 17068132.
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    4. Xu Y, Etgen GJ, Broderick CL, Canada E, Gonzalez I, Lamar J, Montrose-Rafizadeh C, Oldham BA, Osborne JJ, Xie C, Shi Q, Winneroski LL, York J, Yumibe N, Zink R, Mantlo N. Design and synthesis of dual peroxisome proliferator-activated receptors gamma and delta agonists as novel euglycemic agents with a reduced weight gain profile. J Med Chem. 2006 Sep 21; 49(19):5649-52. PMID: 16970391.
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    5. Wang M, Winneroski LL, Ardecky RJ, Babine RE, Brooks DA, Etgen GJ, Hutchison DR, Kauffman RF, Kunkel A, Mais DE, Montrose-Rafizadeh C, Ogilvie KM, Oldham BA, Peters MK, Rito CJ, Rungta DK, Tripp AE, Wilson SB, Xu Y, Zink RW, McCarthy JR. Conversion of human-selective PPARalpha agonists to human/mouse dual agonists: a molecular modeling analysis. Bioorg Med Chem Lett. 2004 Dec 20; 14(24):6113-6. PMID: 15546740.
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    6. Xu Y, Rito CJ, Etgen GJ, Ardecky RJ, Bean JS, Bensch WR, Bosley JR, Broderick CL, Brooks DA, Dominianni SJ, Hahn PJ, Liu S, Mais DE, Montrose-Rafizadeh C, Ogilvie KM, Oldham BA, Peters M, Rungta DK, Shuker AJ, Stephenson GA, Tripp AE, Wilson SB, Winneroski LL, Zink R, Kauffman RF, McCarthy JR. Design and synthesis of alpha-aryloxy-alpha-methylhydrocinnamic acids: a novel class of dual peroxisome proliferator-activated receptor alpha/gamma agonists. J Med Chem. 2004 May 06; 47(10):2422-5. PMID: 15115385.
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    7. Miller AR, Etgen GJ. Novel peroxisome proliferator-activated receptor ligands for Type 2 diabetes and the metabolic syndrome. Expert Opin Investig Drugs. 2003 Sep; 12(9):1489-500. PMID: 12943493.
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    8. Michellys PY, Ardecky RJ, Chen JH, Crombie DL, Etgen GJ, Faul MM, Faulkner AL, Grese TA, Heyman RA, Karanewsky DS, Klausing K, Leibowitz MD, Liu S, Mais DA, Mapes CM, Marschke KB, Reifel-Miller A, Ogilvie KM, Rungta D, Thompson AW, Tyhonas JS, Boehm MF. Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes. J Med Chem. 2003 Jun 19; 46(13):2683-96. PMID: 12801232.
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    9. Etgen GJ, Mantlo N. PPAR ligands for metabolic disorders. Curr Top Med Chem. 2003; 3(14):1649-61. PMID: 14683520.
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    10. Cao G, Liang Y, Broderick CL, Oldham BA, Beyer TP, Schmidt RJ, Zhang Y, Stayrook KR, Suen C, Otto KA, Miller AR, Dai J, Foxworthy P, Gao H, Ryan TP, Jiang XC, Burris TP, Eacho PI, Etgen GJ. Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis. J Biol Chem. 2003 Jan 10; 278(2):1131-6. PMID: 12414791.
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    11. Etgen GJ, Oldham BA, Johnson WT, Broderick CL, Montrose CR, Brozinick JT, Misener EA, Bean JS, Bensch WR, Brooks DA, Shuker AJ, Rito CJ, McCarthy JR, Ardecky RJ, Tyhonas JS, Dana SL, Bilakovics JM, Paterniti JR, Ogilvie KM, Liu S, Kauffman RF. A tailored therapy for the metabolic syndrome: the dual peroxisome proliferator-activated receptor-alpha/gamma agonist LY465608 ameliorates insulin resistance and diabetic hyperglycemia while improving cardiovascular risk factors in preclinical models. Diabetes. 2002 Apr; 51(4):1083-7. PMID: 11916929.
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    12. Etgen GJ, Oldham BA. Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state. Metabolism. 2000 May; 49(5):684-8. PMID: 10831184.
      View in: PubMed
    13. Etgen GJ, Zavadoski WJ, Holman GD, Gibbs EM. Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice. Biochem J. 1999 Jan 01; 337 ( Pt 1):51-7. PMID: 9854024; PMCID: PMC1219935.
    14. Etgen GJ, Fryburg DA, Gibbs EM. Nitric oxide stimulates skeletal muscle glucose transport through a calcium/contraction- and phosphatidylinositol-3-kinase-independent pathway. Diabetes. 1997 Nov; 46(11):1915-9. PMID: 9356048.
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    15. Etgen GJ, Jensen J, Wilson CM, Hunt DG, Cushman SW, Ivy JL. Exercise training reverses insulin resistance in muscle by enhanced recruitment of GLUT-4 to the cell surface. Am J Physiol. 1997 May; 272(5 Pt 1):E864-9. PMID: 9176187.
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    16. Etgen GJ, Wilson CM, Jensen J, Cushman SW, Ivy JL. Glucose transport and cell surface GLUT-4 protein in skeletal muscle of the obese Zucker rat. Am J Physiol. 1996 Aug; 271(2 Pt 1):E294-301. PMID: 8770023.
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    17. Torgan CE, Etgen GJ, Kang HY, Ivy JL. Fiber type-specific effects of clenbuterol and exercise training on insulin-resistant muscle. J Appl Physiol (1985). 1995 Jul; 79(1):163-7. PMID: 7559215.
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    18. Brozinick JT, Etgen GJ, Yaspelkis BB, Ivy JL. Glucose uptake and GLUT-4 protein distribution in skeletal muscle of the obese Zucker rat. Am J Physiol. 1994 Jul; 267(1 Pt 2):R236-43. PMID: 8048627.
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    19. Brozinick JT, Etgen GJ, Yaspelkis BB, Ivy JL. The effects of muscle contraction and insulin on glucose-transporter translocation in rat skeletal muscle. Biochem J. 1994 Feb 01; 297 ( Pt 3):539-45. PMID: 8110191; PMCID: PMC1137867.
    20. Torgan CE, Etgen GJ, Brozinick JT, Wilcox RE, Ivy JL. Interaction of aerobic exercise training and clenbuterol: effects on insulin-resistant muscle. J Appl Physiol (1985). 1993 Oct; 75(4):1471-6. PMID: 8282592.
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    21. Etgen GJ, Memon AR, Thompson GA, Ivy JL. Insulin- and contraction-stimulated translocation of GTP-binding proteins and GLUT4 protein in skeletal muscle. J Biol Chem. 1993 Sep 25; 268(27):20164-9. PMID: 8376376.
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    22. Brozinick JT, Etgen GJ, Yaspelkis BB, Kang HY, Ivy JL. Effects of exercise training on muscle GLUT-4 protein content and translocation in obese Zucker rats. Am J Physiol. 1993 Sep; 265(3 Pt 1):E419-27. PMID: 8214051.
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    23. Etgen GJ, Farrar RP, Ivy JL. Effect of chronic electrical stimulation on GLUT-4 protein content in fast-twitch muscle. Am J Physiol. 1993 Apr; 264(4 Pt 2):R816-9. PMID: 8476125.
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    24. Etgen GJ, Brozinick JT, Kang HY, Ivy JL. Effects of exercise training on skeletal muscle glucose uptake and transport. Am J Physiol. 1993 Mar; 264(3 Pt 1):C727-33. PMID: 8460676.
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    25. Brozinick JT, Etgen GJ, Yaspelkis BB, Ivy JL. Contraction-activated glucose uptake is normal in insulin-resistant muscle of the obese Zucker rat. J Appl Physiol (1985). 1992 Jul; 73(1):382-7. PMID: 1506395.
      View in: PubMed
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