 Alanine
"Alanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D000409
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| MeSH Number(s) |
D12.125.042
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| Concept/Terms |
Alanine- Alanine
- L-Alanine
- L Alanine
- Alanine, L-Isomer
- Alanine, L Isomer
- L-Isomer Alanine
Abufène- Abufène
- Doms-Adrian Brand of Alanine
- Alanine Doms-Adrian Brand
- Doms Adrian Brand of Alanine
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Below are MeSH descriptors whose meaning is more general than "Alanine".
Below are MeSH descriptors whose meaning is more specific than "Alanine".
This graph shows the total number of publications written about "Alanine" by people in this website by year, and whether "Alanine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alanine" by people in Profiles.
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Do H, Kang CW, Cho JH, Gilbertson SR. Enantioselective Synthesis of (-)-Dysiherbaine. Org Lett. 2015 Aug 21; 17(16):3972-4.
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Vaughan DJ, Millman EE, Godines V, Friedman J, Tran TM, Dai W, Knoll BJ, Clark RB, Moore RH. Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. J Biol Chem. 2006 Mar 17; 281(11):7684-92.
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Li CH, Tu SC. Probing the functionalities of alphaGlu328 and alphaAla74 of Vibrio harveyi luciferase by site-directed mutagenesis and chemical rescue. Biochemistry. 2005 Oct 25; 44(42):13866-73.
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Mustata G, Briggs JM. Cluster analysis of water molecules in alanine racemase and their putative structural role. Protein Eng Des Sel. 2004 Mar; 17(3):223-34.
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Clive DL, Hisaindee S, Coltart DM. Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer. J Org Chem. 2003 Nov 28; 68(24):9247-54.
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Mustata GI, Soares TA, Briggs JM. Molecular dynamics studies of alanine racemase: a structural model for drug design. Biopolymers. 2003 Oct; 70(2):186-200.
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Larkin DC, Martinis SA, Roberts DJ, Fox GE. Ala-His mediated peptide bond formation revisited. Orig Life Evol Biosph. 2001 Dec; 31(6):511-26.
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Singh RA, Zang YC, Shrivastava A, Hong J, Wang GT, Li S, Tejada-Simon MV, Kozovska M, Rivera VM, Zhang JZ. Th1 and Th2 deviation of myelin-autoreactive T cells by altered peptide ligands is associated with reciprocal regulation of Lck, Fyn, and ZAP-70. J Immunol. 1999 Dec 15; 163(12):6393-402.
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Sahl HG, Grossgarten M, Widger WR, Cramer WA, Brandis H. Structural similarities of the staphylococcin-like peptide Pep-5 to the peptide antibiotic nisin. Antimicrob Agents Chemother. 1985 May; 27(5):836-40.
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Garber AJ, Schwartz RJ, Seidel CL, Silvers A, Entman ML. Skeletal muscle protein and amino acid metabolism in hereditary mouse muscular dystrophy. Accelerated protein turnover and increased alanine and glutamine formation and release. J Biol Chem. 1980 Sep 10; 255(17):8315-24.
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