 Desipramine
"Desipramine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
| Descriptor ID |
D003891
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| MeSH Number(s) |
D03.494.240.281
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| Concept/Terms |
Desipramine- Desipramine
- Desmethylimipramine
- Demethylimipramine
Norpramin- Norpramin
- Aventis Brand of Desipramine Hydrochloride
- Aventis Behring Brand of Desipramine Hydrochloride
Nu-Desipramine- Nu-Desipramine
- Nu-Pharm Brand of Desipramine Hydrochloride
- Nu Pharm Brand of Desipramine Hydrochloride
Pertofrane- Pertofrane
- Pertrofran
- Novartis Brand of Desipramine Hydrochloride
- Pertofran
- Rhône-Poulenc Rorer Brand of Desipramine Hydrochloride
- Rhône Poulenc Rorer Brand of Desipramine Hydrochloride
Petylyl- Petylyl
- Temmler Brand of Desipramine Hydrochloride
PMS-Desipramine- PMS-Desipramine
- Pharmascience Brand of Desipramine Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Desipramine".
Below are MeSH descriptors whose meaning is more specific than "Desipramine".
This graph shows the total number of publications written about "Desipramine" by people in this website by year, and whether "Desipramine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1990 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1993 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 |
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Below are the most recent publications written about "Desipramine" by people in Profiles.
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Leal J, Ziedonis D, Kosten T. Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. Drug Alcohol Depend. 1994 Mar; 35(1):31-5.
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Kosten TA, Gawin FH, Kosten TR, Rounsaville BJ. Gender differences in cocaine use and treatment response. J Subst Abuse Treat. 1993 Jan-Feb; 10(1):63-6.
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Kosten T, Gawin FH, Silverman DG, Fleming J, Compton M, Jatlow P, Byck R. Intravenous cocaine challenges during desipramine maintenance. Neuropsychopharmacology. 1992 Nov; 7(3):169-76.
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Ziedonis D, Richardson T, Lee E, Petrakis I, Kosten T. Adjunctive desipramine in the treatment of cocaine abusing schizophrenics. Psychopharmacol Bull. 1992; 28(3):309-14.
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Pickett G, Kosten TR, Gawin FH, Byck R, Fleming J, Silverman D, Kosten TA, Jatlow P. Concurrent effects of acute intravenous cocaine in context of chronic desipramine in humans. NIDA Res Monogr. 1990; 105:508-9.
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Martinez AA, Lokhandwala MF. Evidence for a presynaptic inhibitory action of 5-hydroxytryptamine on sympathetic neurotransmission to the myocardium. Eur J Pharmacol. 1980 May 16; 63(4):303-11.
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Jandhyala BS, Steenberg ML, Perel JM, Manian AA, Buckley JP. Effects of several tricyclic antidepressants on the hemodynamics and myocardial contractility of the anesthetized dogs. Eur J Pharmacol. 1977 Apr 21; 42(4):403-10.
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Lokhandwala MF, Coats JT, Buckley JP. Effects of several catecholamines on sympathetic transmission to the myocardium: role of presynaptic alpha-adrenoceptors. Eur J Pharmacol. 1977 Apr 07; 42(3):257-65.
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Lokhandwala MF, Buckley JP. Analysis of presynaptic inhibitory actions of various dopamine analogs on sympathetic neurotransmission in mongrel dogs. Life Sci. 1977 Feb 01; 20(3):507-16.
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Lokhandwala MF, Buckley JP. Effect of presynaptic alpha-adrenoceptor blockade on responses to cardiac nerve stimulation in anesthetized dogs. Eur J Pharmacol. 1976 Nov; 40(1):183-6.
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