 Enzyme Stability
"Enzyme Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an enzyme retains its structural conformation or its activity when subjected to storage, isolation, and purification or various other physical or chemical manipulations, including proteolytic enzymes and heat.
| Descriptor ID |
D004795
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| MeSH Number(s) |
E05.916.360 G02.111.700.500
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| Concept/Terms |
Enzyme Stability- Enzyme Stability
- Enzyme Stabilities
- Stabilities, Enzyme
- Stability, Enzyme
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Below are MeSH descriptors whose meaning is more general than "Enzyme Stability".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Stability".
This graph shows the total number of publications written about "Enzyme Stability" by people in this website by year, and whether "Enzyme Stability" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Enzyme Stability" by people in Profiles.
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Li Y, Cirino PC. Recent advances in engineering proteins for biocatalysis. Biotechnol Bioeng. 2014 Jul; 111(7):1273-87.
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Liu M, Bender SA, Cuny GD, Sherman W, Glicksman M, Ray SS. Type II kinase inhibitors show an unexpected inhibition mode against Parkinson's disease-linked LRRK2 mutant G2019S. Biochemistry. 2013 Mar 12; 52(10):1725-36.
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Ouertatani-Sakouhi H, Liu M, El-Turk F, Cuny GD, Glicksman MA, Lashuel HA. Kinetic-based high-throughput screening assay to discover novel classes of macrophage migration inhibitory factor inhibitors. J Biomol Screen. 2010 Apr; 15(4):347-58.
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Patnaik D, Glicksman MA, Cuny GD, Stein RL, Higgins JM. Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay. J Biomol Screen. 2008 Dec; 13(10):1025-34.
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Salim S, Eikenburg DC. Role of 90-kDa heat shock protein (Hsp 90) and protein degradation in regulating neuronal levels of G protein-coupled receptor kinase 3. J Pharmacol Exp Ther. 2007 Mar; 320(3):1106-12.
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Gliko O, Neumaier N, Pan W, Haase I, Fischer M, Bacher A, Weinkauf S, Vekilov PG. A metastable prerequisite for the growth of lumazine synthase crystals. J Am Chem Soc. 2005 Mar 16; 127(10):3433-8.
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Russell TR, Demeler B, Tu SC. Kinetic mechanism and quaternary structure of Aminobacter aminovorans NADH:flavin oxidoreductase: an unusual flavin reductase with bound flavin. Biochemistry. 2004 Feb 17; 43(6):1580-90.
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Mursinna RS, Lee KW, Briggs JM, Martinis SA. Molecular dissection of a critical specificity determinant within the amino acid editing domain of leucyl-tRNA synthetase. Biochemistry. 2004 Jan 13; 43(1):155-65.
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Salazar O, Cirino PC, Arnold FH. Thermostabilization of a cytochrome p450 peroxygenase. Chembiochem. 2003 Sep 05; 4(9):891-3.
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Barreca ML, Lee KW, Chimirri A, Briggs JM. Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: mechanism for inhibition and drug resistance. Biophys J. 2003 Mar; 84(3):1450-63.
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