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Patrick Cirino

TitleAssociate Professor
InstitutionUniversity of Houston
DepartmentChemical Engineering
Address4800 Calhoun Rd
Houston TX 77004
Phone713-743-4399
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang Z, Cirino PC. New and improved tools and methods for enhanced biosynthesis of natural products in microorganisms. Curr Opin Biotechnol. 2016 Dec; 42:159-168. PMID: 27284635.
      View in: PubMed
    2. Sharma S, Jaimes-Lizcano YA, McLay RB, Cirino PC, Conrad JC. Subnanometric Roughness Affects the Deposition and Mobile Adhesion of Escherichia coli on Silanized Glass Surfaces. Langmuir. 2016 May 31; 32(21):5422-33. PMID: 27158837.
      View in: PubMed
    3. Frei CS, Wang Z, Qian S, Deutsch S, Sutter M, Cirino PC. Analysis of amino acid substitutions in AraC variants that respond to triacetic acid lactone. Protein Sci. 2016 Apr; 25(4):804-14. PMID: 26749125; PMCID: PMC4941223 [Available on 04/01/17].
    4. Ramesh B, Frei CS, Cirino PC, Varadarajan N. Functional enrichment by direct plasmid recovery after fluorescence activated cell sorting. Biotechniques. 2015 Sep; 59(3):157-61. PMID: 26345509.
      View in: PubMed
    5. Li Y, Cirino PC. Recent advances in engineering proteins for biocatalysis. Biotechnol Bioeng. 2014 Jul; 111(7):1273-87. PMID: 24802032.
      View in: PubMed
    6. Grisewood MJ, Gifford NP, Pantazes RJ, Li Y, Cirino PC, Janik MJ, Maranas CD. OptZyme: computational enzyme redesign using transition state analogues. PLoS One. 2013; 8(10):e75358. PMID: 24116038; PMCID: PMC3792102.
    7. Tang SY, Qian S, Akinterinwa O, Frei CS, Gredell JA, Cirino PC. Screening for enhanced triacetic acid lactone production by recombinant Escherichia coli expressing a designed triacetic acid lactone reporter. J Am Chem Soc. 2013 Jul 10; 135(27):10099-103. PMID: 23786422.
      View in: PubMed
    8. Ramesh B, Sendra VG, Cirino PC, Varadarajan N. Single-cell characterization of autotransporter-mediated Escherichia coli surface display of disulfide bond-containing proteins. J Biol Chem. 2012 Nov 09; 287(46):38580-9. PMID: 23019324; PMCID: PMC3493903.
    9. Gredell JA, Frei CS, Cirino PC. Protein and RNA engineering to customize microbial molecular reporting. Biotechnol J. 2012 Apr; 7(4):477-99. PMID: 22031507.
      View in: PubMed
    10. Chin JW, Cirino PC. Improved NADPH supply for xylitol production by engineered Escherichia coli with glycolytic mutations. Biotechnol Prog. 2011 Mar-Apr; 27(2):333-41. PMID: 21344680.
      View in: PubMed
    11. Chin JW, Cirino PC. Strain engineering strategies for improving whole-cell biocatalysis: engineering Escherichia coli to overproduce xylitol as an example. Methods Mol Biol. 2011; 743:185-203. PMID: 21553192.
      View in: PubMed
    12. Tang SY, Cirino PC. Design and application of a mevalonate-responsive regulatory protein. Angew Chem Int Ed Engl. 2011 Feb 01; 50(5):1084-6. PMID: 21268200.
      View in: PubMed
    13. Akinterinwa O, Cirino PC. Anaerobic obligatory xylitol production in Escherichia coli strains devoid of native fermentation pathways. Appl Environ Microbiol. 2011 Jan; 77(2):706-9. PMID: 21097593; PMCID: PMC3020535.
    14. Fasan R, Crook NC, Peters MW, Meinhold P, Buelter T, Landwehr M, Cirino PC, Arnold FH. Improved product-per-glucose yields in P450-dependent propane biotransformations using engineered Escherichia coli. Biotechnol Bioeng. 2011 Mar; 108(3):500-10. PMID: 21246504.
      View in: PubMed
    15. Tang SY, Cirino PC. Elucidating residue roles in engineered variants of AraC regulatory protein. Protein Sci. 2010 Feb; 19(2):291-8. PMID: 20014443; PMCID: PMC2865714.
    16. Khoury GA, Fazelinia H, Chin JW, Pantazes RJ, Cirino PC, Maranas CD. Computational design of Candida boidinii xylose reductase for altered cofactor specificity. Protein Sci. 2009 Oct; 18(10):2125-38. PMID: 19693930; PMCID: PMC2786976.
    17. Khankal R, Chin JW, Ghosh D, Cirino PC. Transcriptional effects of CRP* expression in Escherichia coli. J Biol Eng. 2009 Aug 24; 3:13. PMID: 19703305; PMCID: PMC2743635.
    18. Chin JW, Khankal R, Monroe CA, Maranas CD, Cirino PC. Analysis of NADPH supply during xylitol production by engineered Escherichia coli. Biotechnol Bioeng. 2009 Jan 01; 102(1):209-20. PMID: 18698648.
      View in: PubMed
    19. Fazelinia H, Cirino PC, Maranas CD. OptGraft: A computational procedure for transferring a binding site onto an existing protein scaffold. Protein Sci. 2009 Jan; 18(1):180-95. PMID: 19177362; PMCID: PMC2708043.
    20. Akinterinwa O, Khankal R, Cirino PC. Metabolic engineering for bioproduction of sugar alcohols. Curr Opin Biotechnol. 2008 Oct; 19(5):461-7. PMID: 18760354.
      View in: PubMed
    21. Weiss LE, Badalamenti JP, Weaver LJ, Tascone AR, Weiss PS, Richard TL, Cirino PC. Engineering motility as a phenotypic response to LuxI/R-dependent quorum sensing in Escherichia coli. Biotechnol Bioeng. 2008 Aug 15; 100(6):1251-5. PMID: 18553406.
      View in: PubMed
    22. Akinterinwa O, Cirino PC. Heterologous expression of D-xylulokinase from Pichia stipitis enables high levels of xylitol production by engineered Escherichia coli growing on xylose. Metab Eng. 2009 Jan; 11(1):48-55. PMID: 18723107.
      View in: PubMed
    23. Khankal R, Luziatelli F, Chin JW, Frei CS, Cirino PC. Comparison between Escherichia coli K-12 strains W3110 and MG1655 and wild-type E. coli B as platforms for xylitol production. Biotechnol Lett. 2008 Sep; 30(9):1645-53. PMID: 18414795.
      View in: PubMed
    24. Tang SY, Fazelinia H, Cirino PC. AraC regulatory protein mutants with altered effector specificity. J Am Chem Soc. 2008 Apr 16; 130(15):5267-71. PMID: 18355019.
      View in: PubMed
    25. Cirino PC, Sun L. Advancing biocatalysis through enzyme, cellular, and platform engineering. Biotechnol Prog. 2008 May-Jun; 24(3):515-9. PMID: 18335955.
      View in: PubMed
    26. Khankal R, Chin JW, Cirino PC. Role of xylose transporters in xylitol production from engineered Escherichia coli. J Biotechnol. 2008 Apr 30; 134(3-4):246-52. PMID: 18359531.
      View in: PubMed
    27. Fazelinia H, Cirino PC, Maranas CD. Extending Iterative Protein Redesign and Optimization (IPRO) in protein library design for ligand specificity. Biophys J. 2007 Mar 15; 92(6):2120-30. PMID: 17208966; PMCID: PMC1861794.
    28. Cirino PC, Chin JW, Ingram LO. Engineering Escherichia coli for xylitol production from glucose-xylose mixtures. Biotechnol Bioeng. 2006 Dec 20; 95(6):1167-76. PMID: 16838379.
      View in: PubMed
    29. Cirino PC, Tang Y, Takahashi K, Tirrell DA, Arnold FH. Global incorporation of norleucine in place of methionine in cytochrome P450 BM-3 heme domain increases peroxygenase activity. Biotechnol Bioeng. 2003 Sep 20; 83(6):729-34. PMID: 12889037.
      View in: PubMed
    30. Salazar O, Cirino PC, Arnold FH. Thermostabilization of a cytochrome p450 peroxygenase. Chembiochem. 2003 Sep 05; 4(9):891-3. PMID: 12964165.
      View in: PubMed
    31. Cirino PC, Arnold FH. A self-sufficient peroxide-driven hydroxylation biocatalyst. Angew Chem Int Ed Engl. 2003 Jul 21; 42(28):3299-301. PMID: 12876749.
      View in: PubMed
    32. Cirino PC, Georgescu R. Screening for thermostability. Methods Mol Biol. 2003; 230:117-25. PMID: 12824574.
      View in: PubMed
    33. Cirino PC, Mayer KM, Umeno D. Generating mutant libraries using error-prone PCR. Methods Mol Biol. 2003; 231:3-9. PMID: 12824595.
      View in: PubMed
    34. Cirino PC, Arnold FH. Protein engineering of oxygenases for biocatalysis. Curr Opin Chem Biol. 2002 Apr; 6(2):130-5. PMID: 12038995.
      View in: PubMed
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