Indomethacin
"Indomethacin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
Descriptor ID |
D007213
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MeSH Number(s) |
D03.438.473.420
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Indomethacin".
Below are MeSH descriptors whose meaning is more specific than "Indomethacin".
This graph shows the total number of publications written about "Indomethacin" by people in this website by year, and whether "Indomethacin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1982 | 0 | 1 | 1 | 1988 | 0 | 2 | 2 | 1990 | 0 | 1 | 1 | 1992 | 0 | 2 | 2 | 1993 | 0 | 2 | 2 | 2006 | 1 | 0 | 1 | 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Indomethacin" by people in Profiles.
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Sokoya EM, Burns AR, Marrelli SP, Chen J. Myoendothelial gap junction frequency does not account for sex differences in EDHF responses in rat MCA. Microvasc Res. 2007 Jul; 74(1):39-44.
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Birkinshaw TN, Teague SJ, Beech C, Bonnert RV, Hill S, Patel A, Reakes S, Sanganee H, Dougall IG, Phillips TT, Salter S, Schmidt J, Arrowsmith EC, Carrillo JJ, Bell FM, Paine SW, Weaver R. Discovery of potent CRTh2 (DP2) receptor antagonists. Bioorg Med Chem Lett. 2006 Aug 15; 16(16):4287-90.
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Sadeghi HM, Eikenburg DC. Is sympathetic neurotransmission in the rat mesentery modulated by prejunctional beta adrenoceptors? J Pharmacol Exp Ther. 1993 May; 265(2):657-63.
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James MJ, Birmingham AT, Hill SJ. Partial mediation by nitric oxide of the relaxation of human isolated detrusor strips in response to electrical field stimulation. Br J Clin Pharmacol. 1993 Apr; 35(4):366-72.
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White TE, Dickenson JM, Alexander SP, Hill SJ. Adenosine A1-receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT1 MF-2 cells. Br J Pharmacol. 1992 May; 106(1):215-21.
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Contractor CP, Mehta SD, Wagle SU, Desphande PG, Irani SF. Bartter's syndrome: a neonatal presentation (a case report). J Postgrad Med. 1992 Jan-Mar; 38(1):41-3.
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George FR, Meisch RA. Cyclooxygenase inhibitors antagonize the rate-depressant effects of ethanol on fixed-ratio responding. Alcohol. 1990 Jul-Aug; 7(4):355-60.
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Robleto DO, Reitmeyer ST, Herman CA. Cardiac inotropic effects of leukotriene C4 and prostaglandin I2 in the unanesthetized American bullfrog, Rana catesbeiana. Can J Physiol Pharmacol. 1988 Mar; 66(3):233-8.
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Herman CA, Robleto DO, Reitmeyer ST, Martinez LA, Herman RP. Cardiovascular effects of leukotrienes in the bullfrog. Biomed Biochim Acta. 1988; 47(10-11):S178-81.
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Hamed AT, Lokhandwala MF. Impairment of neurally-mediated vasoconstriction in DOCA-salt hypertensive dogs. Clin Exp Hypertens A. 1982; 4(6):867-81.
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