Methylation
"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
Descriptor ID |
D008745
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MeSH Number(s) |
G02.111.087.029.538 G02.149.115.029.538 G02.149.465.040.538 G02.607.750.040.538 G03.495.130.538
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1987 | 0 | 1 | 1 | 1989 | 0 | 1 | 1 | 1991 | 0 | 1 | 1 | 1995 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2009 | 0 | 2 | 2 | 2012 | 0 | 2 | 2 | 2013 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylation" by people in Profiles.
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Huang C, Cheng J, Bawa-Khalfe T, Yao X, Chin YE, Yeh ET. SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability. Cell Rep. 2016 Apr 05; 15(1):147-57.
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Rasmussen TL, Ma Y, Park CY, Harriss J, Pierce SA, Dekker JD, Valenzuela N, Srivastava D, Schwartz RJ, Stewart MD, Tucker HO. Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses. PLoS One. 2015; 10(3):e0121765.
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Tiwari S, Dharmarajan S, Shivanna M, Otteson DC, Belecky-Adams TL. Histone deacetylase expression patterns in developing murine optic nerve. BMC Dev Biol. 2014 Jul 09; 14:30.
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Tennakoon JB, Wang H, Coarfa C, Cooney AJ, Gunaratne PH. Chromatin changes in dicer-deficient mouse embryonic stem cells in response to retinoic acid induced differentiation. PLoS One. 2013; 8(9):e74556.
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Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ. Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Electrophoresis. 2012 Jul; 33(12):1873-80.
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Xu Z, He Y, Ju J, Rank G, Cerruti L, Ma C, Simpson RJ, Moritz RL, Jane SM, Zhao Q. The role of WDR5 in silencing human fetal globin gene expression. Haematologica. 2012 Nov; 97(11):1632-40.
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Reisenauer MR, Anderson M, Huang L, Zhang Z, Zhou Q, Kone BC, Morris AP, Lesage GD, Dryer SE, Zhang W. AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha. J Biol Chem. 2009 Dec 18; 284(51):35659-69.
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Nimura K, Ura K, Shiratori H, Ikawa M, Okabe M, Schwartz RJ, Kaneda Y. A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature. 2009 Jul 09; 460(7252):287-91.
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Teng X, Degterev A, Jagtap P, Xing X, Choi S, Denu R, Yuan J, Cuny GD. Structure-activity relationship study of novel necroptosis inhibitors. Bioorg Med Chem Lett. 2005 Nov 15; 15(22):5039-44.
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Coltart DM, Danishefsky SJ. Novel synthetic approach to the 8,10-dimethyl anti-syn-anti-perhydrophenanthrene skeleton. Org Lett. 2003 Apr 17; 5(8):1289-92.
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