 Phosphodiesterase Inhibitors
"Phosphodiesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
| Descriptor ID |
D010726
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| MeSH Number(s) |
D27.505.519.389.735
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| Concept/Terms |
Phosphodiesterase Inhibitors- Phosphodiesterase Inhibitors
- Phosphodiesterase Antagonists
- Phosphoric Diester Hydrolase Inhibitors
- Antiphosphodiesterases
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Below are MeSH descriptors whose meaning is more general than "Phosphodiesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Phosphodiesterase Inhibitors".
This graph shows the total number of publications written about "Phosphodiesterase Inhibitors" by people in this website by year, and whether "Phosphodiesterase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 1 | 1 | 2 | | 1989 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 |
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Below are the most recent publications written about "Phosphodiesterase Inhibitors" by people in Profiles.
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Anderson M, Kim EY, Hagmann H, Benzing T, Dryer SE. Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol. Am J Physiol Cell Physiol. 2013 Aug 01; 305(3):C276-89.
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Thomson G, Watson A, Caldecott K, Denneny O, Depledge P, Hamilton N, Hopkins G, Jordan A, Morrow C, Raoof A, Waddell I, Ogilvie D. Generation of assays and antibodies to facilitate the study of human 5'-tyrosyl DNA phosphodiesterase. Anal Biochem. 2013 May 15; 436(2):145-50.
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Xu H, Kulkarni KH, Singh R, Yang Z, Wang SW, Tam VH, Hu M. Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides. Mol Pharm. 2009 Nov-Dec; 6(6):1703-15.
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Hogan YH, Florent G, Hussain T, Alkadhi KA. Cyclic AMP antagonizes adenosine-induced inhibition of ganglionic transmission. Brain Res. 1998 Mar 23; 787(2):242-7.
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D'Souza T, Dryer SE. Effects of phosphodiesterase inhibitors and forskolin on cyclic GMP-activated channels in intact isolated cells of the chick pineal gland. Neurochem Int. 1995 Dec; 27(6):527-33.
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Dickenson JM, White TE, Hill SJ. The effects of elevated cyclic AMP levels on histamine-H1-receptor-stimulated inositol phospholipid hydrolysis and calcium mobilization in the smooth-muscle cell line DDT1MF-2. Biochem J. 1993 Jun 01; 292 ( Pt 2):409-17.
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Hall IP, Hill SJ. Effects of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone. Biochem Pharmacol. 1992 Jan 09; 43(1):15-7.
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Hall IP, Donaldson J, Hill SJ. Inhibition of histamine-stimulated inositol phospholipid hydrolysis by agents which increase cyclic AMP levels in bovine tracheal smooth muscle. Br J Pharmacol. 1989 Jun; 97(2):603-13.
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Donaldson J, Hill SJ, Brown AM. Kinetic studies on the mechanism by which histamine H1 receptors potentiate cyclic AMP accumulation in guinea pig cerebral cortical slices. Mol Pharmacol. 1988 Jun; 33(6):626-33.
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Donaldson J, Brown AM, Hill SJ. Influence of rolipram on the cyclic 3',5'-adenosine monophosphate response to histamine and adenosine in slices of guinea-pig cerebral cortex. Biochem Pharmacol. 1988 Feb 15; 37(4):715-23.
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