Prazosin
"Prazosin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
| Descriptor ID |
D011224
|
| MeSH Number(s) |
D03.438.786.750
|
| Concept/Terms |
Minipress- Minipress
- Pfizer Brand of Prazosin Hydrochloride
Pratsiol- Pratsiol
- Douglas Brand of Prazosin Hydrochloride
|
Below are MeSH descriptors whose meaning is more general than "Prazosin".
Below are MeSH descriptors whose meaning is more specific than "Prazosin".
This graph shows the total number of publications written about "Prazosin" by people in this website by year, and whether "Prazosin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 |
| 1986 | 0 | 1 | 1 |
| 1991 | 0 | 1 | 1 |
| 1993 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prazosin" by people in Profiles.
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Zhang XY, Kosten TA. Previous exposure to cocaine enhances cocaine self-administration in an alpha 1-adrenergic receptor dependent manner. Neuropsychopharmacology. 2007 Mar; 32(3):638-45.
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Zhang XY, Kosten TA. Prazosin, an alpha-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking. Biol Psychiatry. 2005 May 15; 57(10):1202-4.
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Gopalakrishnan SM, Chen C, Lokhandwala MF. Identification of alpha 1-adrenoceptor subtypes in rat renal proximal tubules. Eur J Pharmacol. 1993 Dec 21; 250(3):469-72.
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Ruck A, Kendall DA, Hill SJ. Alpha- and beta-adrenoceptor regulation of cyclic AMP accumulation in cultured rat astrocytes. A comparison of primary protoplasmic and mixed fibrous/protoplasmic astroglial cultures. Biochem Pharmacol. 1991 Jun 21; 42(1):59-69.
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Hamed AT, Jandhyala BS, Lokhandwala MF. Evaluation of the role of alpha-1 and alpha-2 adrenoceptors in the maintenance of neurogenic tone to the hindlimb vasculature. J Pharmacol Exp Ther. 1986 Aug; 238(2):599-605.
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Eikenburg DC. Functional characterization of the pre- and postjunctional alpha-adrenoceptors in the in situ perfused rat mesenteric vascular bed. Eur J Pharmacol. 1984 Oct 01; 105(1-2):161-5.
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Hardey DW, Lokhandwala MF. Influence of prazosin on cardiac reflex function. Eur J Pharmacol. 1979 Aug 01; 57(2-3):251-4.