Pyruvate Dehydrogenase Complex
"Pyruvate Dehydrogenase Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
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A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE); dihydrolipoamide acetyltransferase; and LIPOAMIDE DEHYDROGENASE. Pyruvate dehydrogenase complex is subject to three types of control: inhibited by acetyl-CoA and NADH; influenced by the energy state of the cell; and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE catalyzes reactivation of the complex. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
| Descriptor ID |
D011768
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| MeSH Number(s) |
D05.500.562.625 D08.811.600.741
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| Concept/Terms |
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This graph shows the total number of publications written about "Pyruvate Dehydrogenase Complex" by people in this website by year, and whether "Pyruvate Dehydrogenase Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyruvate Dehydrogenase Complex" by people in Profiles.
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Marillia EF, Micallef BJ, Micallef M, Weninger A, Pedersen KK, Zou J, Taylor DC. Biochemical and physiological studies of Arabidopsis thaliana transgenic lines with repressed expression of the mitochondrial pyruvate dehydrogenase kinase. J Exp Bot. 2003 Jan; 54(381):259-70.
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Zou J, Qi Q, Katavic V, Marillia EF, Taylor DC. Effects of antisense repression of an Arabidopsis thaliana pyruvate dehydrogenase kinase cDNA on plant development. Plant Mol Biol. 1999 Dec; 41(6):837-49.