Receptors, Histamine
"Receptors, Histamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell-surface proteins that bind histamine and trigger intracellular changes influencing the behavior of cells. Histamine receptors are widespread in the central nervous system and in peripheral tissues. Three types have been recognized and designated H1, H2, and H3. They differ in pharmacology, distribution, and mode of action.
Descriptor ID |
D011968
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MeSH Number(s) |
D12.776.543.750.069.450 D12.776.543.750.720.480
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, Histamine".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Histamine".
This graph shows the total number of publications written about "Receptors, Histamine" by people in this website by year, and whether "Receptors, Histamine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1980 | 1 | 0 | 1 | 1981 | 2 | 0 | 2 | 1982 | 1 | 0 | 1 | 1984 | 1 | 0 | 1 | 1985 | 1 | 0 | 1 | 1986 | 3 | 0 | 3 | 1987 | 1 | 0 | 1 | 1988 | 1 | 0 | 1 | 1990 | 3 | 0 | 3 | 1991 | 1 | 0 | 1 | 1992 | 1 | 0 | 1 | 1995 | 1 | 0 | 1 | 1997 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Histamine" by people in Profiles.
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Hill SJ, Ganellin CR, Timmerman H, Schwartz JC, Shankley NP, Young JM, Schunack W, Levi R, Haas HL. International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol Rev. 1997 Sep; 49(3):253-78.
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Nowak JZ, Sek B, D'Souza T, Dryer SE. Does histamine stimulate cyclic AMP formation in the avian pineal gland via a novel (non-H1, non-H2, non-H3) histamine receptor subtype. Neurochem Int. 1995 Dec; 27(6):519-26.
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Hill SJ. Multiple histamine receptors: properties and functional characteristics. Biochem Soc Trans. 1992 Feb; 20(1):122-5.
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Hill SJ. Histamine receptors and interactions between second messenger transduction systems. Agents Actions Suppl. 1991; 33:145-59.
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Hew RW, Hodgkinson CR, Hill SJ. Characterization of histamine H3-receptors in guinea-pig ileum with H3-selective ligands. Br J Pharmacol. 1990 Nov; 101(3):621-4.
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Ottosson A, Hill SJ, Edvinsson L. Histamine receptors in brain vessels of guinea-pig: in-vitro pharmacology and ligand binding. Acta Physiol Scand. 1990 Sep; 140(1):135-41.
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Hill SJ. Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol Rev. 1990 Mar; 42(1):45-83.
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Donaldson J, Hill SJ, Brown AM. Kinetic studies on the mechanism by which histamine H1 receptors potentiate cyclic AMP accumulation in guinea pig cerebral cortical slices. Mol Pharmacol. 1988 Jun; 33(6):626-33.
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Donaldson J, Hill SJ. 1,4-Dithiothreitol-induced changes in histamine H1-agonist efficacy and affinity in the longitudinal smooth muscle of guinea-pig ileum. Br J Pharmacol. 1987 Jan; 90(1):263-71.
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Donaldson J, Hill SJ. Enhancement of histamine H1-receptor agonist activity by 1,4-dithiothreitol in guinea-pig cerebellum and cerebral cortex. J Neurochem. 1986 Nov; 47(5):1476-82.
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