 Receptor, Insulin
"Receptor, Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.
| Descriptor ID |
D011972
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.200 D12.776.543.750.060.484 D12.776.543.750.750.580.300
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| Concept/Terms |
Receptor, Insulin- Receptor, Insulin
- Insulin Receptor Protein-Tyrosine Kinase
- Insulin Receptor Protein Tyrosine Kinase
- Receptors, Insulin
- Insulin Receptors
- Insulin Receptor
- Insulin-Dependent Tyrosine Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "Receptor, Insulin".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Insulin".
This graph shows the total number of publications written about "Receptor, Insulin" by people in this website by year, and whether "Receptor, Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Insulin" by people in Profiles.
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Ritchey ER, Zelinka CP, Tang J, Liu J, Fischer AJ. The combination of IGF1 and FGF2 and the induction of excessive ocular growth and extreme myopia. Exp Eye Res. 2012 Jun; 99:1-16.
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Davidson CM, Northrup H, King TM, Fletcher JM, Townsend I, Tyerman GH, Au KS. Genes in glucose metabolism and association with spina bifida. Reprod Sci. 2008 Jan; 15(1):51-8.
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Rajala A, Anderson RE, Ma JX, Lem J, Al-Ubaidi MR, Rajala RV. G-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptor. J Biol Chem. 2007 Mar 30; 282(13):9865-73.
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Hitchcock PF, Otteson DC, Cirenza PF. Expression of the insulin receptor in the retina of the goldfish. Invest Ophthalmol Vis Sci. 2001 Aug; 42(9):2125-9.
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