 Synapses
"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
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| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 2 | 2 | | 1982 | 0 | 1 | 1 | | 1983 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1988 | 1 | 0 | 1 | | 1989 | 1 | 0 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 2 | 1 | 3 | | 2008 | 1 | 3 | 4 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 3 | 5 | | 2011 | 1 | 2 | 3 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 0 | 2 | 2 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Veliz-Cuba A, Shouval HZ, Josic K, Kilpatrick ZP. Networks that learn the precise timing of event sequences. J Comput Neurosci. 2015 Dec; 39(3):235-54.
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Schwarz LA, Miyamichi K, Gao XJ, Beier KT, Weissbourd B, DeLoach KE, Ren J, Ibanes S, Malenka RC, Kremer EJ, Luo L. Viral-genetic tracing of the input-output organization of a central noradrenaline circuit. Nature. 2015 Aug 06; 524(7563):88-92.
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Scudder SL, Goo MS, Cartier AE, Molteni A, Schwarz LA, Wright R, Patrick GN. Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8. J Neurosci. 2014 Dec 10; 34(50):16637-49.
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Chadderdon GL, Mohan A, Suter BA, Neymotin SA, Kerr CC, Francis JT, Shepherd GM, Lytton WW. Motor cortex microcircuit simulation based on brain activity mapping. Neural Comput. 2014 Jul; 26(7):1239-62.
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Blair MG, Nguyen NN, Albani SH, L'Etoile MM, Andrawis MM, Owen LM, Oliveira RF, Johnson MW, Purvis DL, Sanders EM, Stoneham ET, Xu H, Dumas TC. Developmental changes in structural and functional properties of hippocampal AMPARs parallels the emergence of deliberative spatial navigation in juvenile rats. J Neurosci. 2013 Jul 24; 33(30):12218-28.
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Butler K, Martinez LA, Tejada-Simon MV. Impaired cognitive function and reduced anxiety-related behavior in a promyelocytic leukemia (PML) tumor suppressor protein-deficient mouse. Genes Brain Behav. 2013 Mar; 12(2):189-202.
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Schwarz LA, Patrick GN. Ubiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins. Mol Cell Neurosci. 2012 Mar; 49(3):387-93.
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Kilpatrick ZP, Bard Ermentrout G. Hallucinogen persisting perception disorder in neuronal networks with adaptation. J Comput Neurosci. 2012 Feb; 32(1):25-53.
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Bongmba OY, Martinez LA, Elhardt ME, Butler K, Tejada-Simon MV. Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology. Brain Res. 2011 Jul 05; 1399:79-95.
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Sherry DM, Murray AR, Kanan Y, Arbogast KL, Hamilton RA, Fliesler SJ, Burns ME, Moore KL, Al-Ubaidi MR. Lack of protein-tyrosine sulfation disrupts photoreceptor outer segment morphogenesis, retinal function and retinal anatomy. Eur J Neurosci. 2010 Nov; 32(9):1461-72.
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