Antigens, CD4
"Antigens, CD4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
Descriptor ID |
D015704
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MeSH Number(s) |
D12.776.543.750.705.852.420.810.500 D12.776.543.750.925.700.025 D23.050.301.264.035.104 D23.050.301.264.894.100 D23.101.100.110.104 D23.101.100.894.100
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Concept/Terms |
Antigens, CD4- Antigens, CD4
- CD4 Receptors
- Receptors, CD4
- T4 Antigens, T-Cell
- Antigens, T-Cell T4
- T-Cell T4 Antigens
- T4 Antigens, T Cell
- Surface CD4 Receptor
- CD4 Receptor, Surface
- CD4 Antigen
- Antigen, CD4
- CD4 Antigens
- CD4 Molecule
- Receptors, Surface CD4
- CD4 Receptors, Surface
- Surface CD4 Receptors
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Below are MeSH descriptors whose meaning is more general than "Antigens, CD4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-16 [D12.776.543.750.705.852.420.810]
- Antigens, CD4 [D12.776.543.750.705.852.420.810.500]
- Receptors, Virus [D12.776.543.750.925]
- Receptors, HIV [D12.776.543.750.925.700]
- Antigens, CD4 [D12.776.543.750.925.700.025]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, CD [D23.050.301.264.035]
- Antigens, CD4 [D23.050.301.264.035.104]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- Antigens, CD4 [D23.050.301.264.894.100]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, CD [D23.101.100.110]
- Antigens, CD4 [D23.101.100.110.104]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- Antigens, CD4 [D23.101.100.894.100]
Below are MeSH descriptors whose meaning is more specific than "Antigens, CD4".
This graph shows the total number of publications written about "Antigens, CD4" by people in this website by year, and whether "Antigens, CD4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1990 | 0 | 1 | 1 | 1991 | 1 | 0 | 1 | 1992 | 2 | 0 | 2 | 2002 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2009 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Antigens, CD4" by people in Profiles.
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Brown FF, Bigley AB, Ross JC, LaVoy EC, Simpson RJ, Galloway SD. T-lymphocyte populations following a period of high volume training in female soccer players. Physiol Behav. 2015 Dec 01; 152(Pt A):175-81.
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Woods SP, Iudicello JE, Dawson MS, Weber E, Grant I, Letendre SL. HIV-associated deficits in action (verb) generation may reflect astrocytosis. J Clin Exp Neuropsychol. 2010 Jun; 32(5):522-7.
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Waid DM, Vaitaitis GM, Pennock ND, Wagner DH. Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes. J Leukoc Biol. 2008 Aug; 84(2):431-9.
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Carey CL, Woods SP, Rippeth JD, Gonzalez R, Heaton RK, Grant I. Additive deleterious effects of methamphetamine dependence and immunosuppression on neuropsychological functioning in HIV infection. AIDS Behav. 2006 Mar; 10(2):185-90.
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Wagner DH, Vaitaitis G, Sanderson R, Poulin M, Dobbs C, Haskins K. Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3782-7.
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Eichberg JW, Murthy KK, Ward RH, Prince AM. Prevention of HIV infection by passive immunization with HIVIG or CD4-IgG. AIDS Res Hum Retroviruses. 1992 Aug; 8(8):1515.
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Chamow SM, Duliege AM, Ammann A, Kahn JO, Allen JD, Eichberg JW, Byrn RA, Capon DJ, Ward RH, Ashkenazi A. CD4 immunoadhesins in anti-HIV therapy: new developments. Int J Cancer Suppl. 1992; 7:69-72.
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Ward RH, Capon DJ, Jett CM, Murthy KK, Mordenti J, Lucas C, Frie SW, Prince AM, Green JD, Eichberg JW. Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesin. Nature. 1991 Aug 01; 352(6334):434-6.
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Berman PW, Gregory TJ, Riddle L, Nakamura GR, Champe MA, Porter JP, Wurm FM, Hershberg RD, Cobb EK, Eichberg JW. Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160. Nature. 1990 Jun 14; 345(6276):622-5.
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