 Receptors, CCR5
"Receptors, CCR5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; MACROPHAGES; MAST CELLS; and NK CELLS. The CCR5 receptor is used by the HUMAN IMMUNODEFICIENCY VIRUS to infect cells.
| Descriptor ID |
D019713
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| MeSH Number(s) |
D12.776.543.750.100.160.150.500 D12.776.543.750.705.852.125.150.500 D12.776.543.750.925.700.605 D23.050.301.264.035.605.150.500 D23.101.100.110.605.150.500
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| Concept/Terms |
Receptors, CCR5- Receptors, CCR5
- CC Chemokine Receptor 5
- CC-CKR5
- Receptors, CKR5
- CCR5 Receptors
- CD195 Antigens
- CKR5 Receptors
- Antigens, CD195
- CCR5 Receptor
- Receptor, CCR5
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Below are MeSH descriptors whose meaning is more general than "Receptors, CCR5".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Chemokine [D12.776.543.750.100.160]
- Receptors, CCR [D12.776.543.750.100.160.150]
- Receptors, CCR5 [D12.776.543.750.100.160.150.500]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Chemokine [D12.776.543.750.705.852.125]
- Receptors, CCR [D12.776.543.750.705.852.125.150]
- Receptors, CCR5 [D12.776.543.750.705.852.125.150.500]
- Receptors, Virus [D12.776.543.750.925]
- Receptors, HIV [D12.776.543.750.925.700]
- Receptors, CCR5 [D12.776.543.750.925.700.605]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, CD [D23.050.301.264.035]
- Receptors, Chemokine [D23.050.301.264.035.605]
- Receptors, CCR [D23.050.301.264.035.605.150]
- Receptors, CCR5 [D23.050.301.264.035.605.150.500]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, CD [D23.101.100.110]
- Receptors, Chemokine [D23.101.100.110.605]
- Receptors, CCR [D23.101.100.110.605.150]
- Receptors, CCR5 [D23.101.100.110.605.150.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, CCR5".
This graph shows the total number of publications written about "Receptors, CCR5" by people in this website by year, and whether "Receptors, CCR5" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, CCR5" by people in Profiles.
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Schwehm C, Kellam B, Garces AE, Hill SJ, Kindon ND, Bradshaw TD, Li J, Macdonald SJ, Rowedder JE, Stoddart LA, Stocks MJ. Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase d (PI3Kd) Inhibitors. J Med Chem. 2017 Feb 23; 60(4):1534-1554.
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Morris SR, Woods SP, Deutsch R, Little SJ, Wagner G, Morgan EE, Heaton RK, Letendre SL, Grant I, Smith DM. Dual-mixed HIV-1 coreceptor tropism and HIV-associated neurocognitive deficits. J Neurovirol. 2013 Oct; 19(5):488-94.
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Shigeta A, Tada Y, Wang JY, Ishizaki S, Tsuyusaki J, Yamauchi K, Kasahara Y, Iesato K, Tanabe N, Takiguchi Y, Sakamoto A, Tokuhisa T, Shibuya K, Hiroshima K, West J, Tatsumi K. CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema. Am J Physiol Lung Cell Mol Physiol. 2012 Jul; 303(2):L141-51.
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Wang F, Xiu MH, Zhou DF, Cao LY, Wu GY, Kosten TA, Kosten TR, Zhang XY. The CCR5 32-bp deletion allele is rare in a Chinese population. Schizophr Res. 2008 Apr; 101(1-3):341-3.
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Longden J, Cooke EL, Hill SJ. Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO-K1 cells. Br J Pharmacol. 2008 Apr; 153(7):1513-27.
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Ball SC, Abraha A, Collins KR, Marozsan AJ, Baird H, Quiñones-Mateu ME, Penn-Nicholson A, Murray M, Richard N, Lobritz M, Zimmerman PA, Kawamura T, Blauvelt A, Arts EJ. Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C. J Virol. 2003 Jan; 77(2):1021-38.
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Zang YC, Samanta AK, Halder JB, Hong J, Tejada-Simon MV, Rivera VM, Zhang JZ. Aberrant T cell migration toward RANTES and MIP-1 alpha in patients with multiple sclerosis. Overexpression of chemokine receptor CCR5. Brain. 2000 Sep; 123 ( Pt 9):1874-82.
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ten Haaft PJ, Murthy KK, Verstrepen BE, Eichberg JW, Heeney JL. Intact CCR-5 coreceptors in HIV-1-infected chimpanzees. AIDS. 1997 Aug; 11(10):1291-3.
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