 alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
"alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
| Descriptor ID |
D018350
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| MeSH Number(s) |
D03.383.129.385.025
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid".
Below are MeSH descriptors whose meaning is more specific than "alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid".
This graph shows the total number of publications written about "alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid" by people in this website by year, and whether "alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1990 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 |
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Below are the most recent publications written about "alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid" by people in Profiles.
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Schwarz LA, Hall BJ, Patrick GN. Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway. J Neurosci. 2010 Dec 08; 30(49):16718-29.
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Kasai N, Ramanujan CS, Fujimoto I, Shimada A, Ryan JF, Torimitsu K. AFM observation of single, functioning ionotropic glutamate receptors reconstituted in lipid bilayers. Biochim Biophys Acta. 2010 Jul; 1800(7):655-61.
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Alexander SP, Curtis AR, Hill SJ, Kendall DA. Activation of a metabotropic excitatory amino acid receptor potentiates A2b adenosine receptor-stimulated cyclic AMP accumulation. Neurosci Lett. 1992 Nov 09; 146(2):231-3.
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Alexander SP, Hill SJ, Kendall DA. Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors? J Neurochem. 1990 Oct; 55(4):1439-41.
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