 Th1 Cells
"Th1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.
| Descriptor ID |
D018417
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| MeSH Number(s) |
A11.118.637.555.567.550.500.400.900 A11.118.637.555.567.569.200.400.900 A11.118.637.555.567.569.500.400.900 A15.145.229.637.555.567.550.500.400.500 A15.145.229.637.555.567.569.200.400.500 A15.145.229.637.555.567.569.500.400.500 A15.382.490.555.567.550.500.400.900 A15.382.490.555.567.569.200.400.900 A15.382.490.555.567.569.500.400.900
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| Concept/Terms |
Th1 Cells- Th1 Cells
- Cell, Th1
- Cells, Th1
- Th1 Cell
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Below are MeSH descriptors whose meaning is more general than "Th1 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th1 Cells [A11.118.637.555.567.550.500.400.900]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th1 Cells [A11.118.637.555.567.569.200.400.900]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th1 Cells [A11.118.637.555.567.569.500.400.900]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th1 Cells [A15.145.229.637.555.567.550.500.400.500]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th1 Cells [A15.145.229.637.555.567.569.200.400.500]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th1 Cells [A15.145.229.637.555.567.569.500.400.500]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th1 Cells [A15.382.490.555.567.550.500.400.900]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th1 Cells [A15.382.490.555.567.569.200.400.900]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th1 Cells [A15.382.490.555.567.569.500.400.900]
Below are MeSH descriptors whose meaning is more specific than "Th1 Cells".
This graph shows the total number of publications written about "Th1 Cells" by people in this website by year, and whether "Th1 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Th1 Cells" by people in Profiles.
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Qin X, Guo BT, Wan B, Fang L, Lu L, Wu L, Zang YQ, Zhang JZ. Regulation of Th1 and Th17 cell differentiation and amelioration of experimental autoimmune encephalomyelitis by natural product compound berberine. J Immunol. 2010 Aug 01; 185(3):1855-63.
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Ryeom S, Greenwald RJ, Sharpe AH, McKeon F. The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin. Nat Immunol. 2003 Sep; 4(9):874-81.
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Wagner DH, Vaitaitis G, Sanderson R, Poulin M, Dobbs C, Haskins K. Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3782-7.
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Tejada-Simon MV, Zang YC, Yang D, Hong J, Li S, Singh RA, Van den Berg-Loonen E, Killian JM, Rivera VM, Zhang JZ. Aberrant T cell responses to myelin antigens during clinical exacerbation in patients with multiple sclerosis. Int Immunol. 2000 Dec; 12(12):1641-50.
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Singh RA, Zang YC, Shrivastava A, Hong J, Wang GT, Li S, Tejada-Simon MV, Kozovska M, Rivera VM, Zhang JZ. Th1 and Th2 deviation of myelin-autoreactive T cells by altered peptide ligands is associated with reciprocal regulation of Lck, Fyn, and ZAP-70. J Immunol. 1999 Dec 15; 163(12):6393-402.
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Huber SA, Stone JE, Wagner DH, Kupperman J, Pfeiffer L, David C, O'Brien RL, Davis GS, Newell MK. gamma delta+ T cells regulate major histocompatibility complex class II(IA and IE)-dependent susceptibility to coxsackievirus B3-induced autoimmune myocarditis. J Virol. 1999 Jul; 73(7):5630-6.
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