 src-Family Kinases
"src-Family Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
| Descriptor ID |
D019061
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| MeSH Number(s) |
D08.811.913.696.620.682.725.800
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| Concept/Terms |
src-Family Kinases- src-Family Kinases
- src Family Kinases
- src-Family Tyrosine Kinases
- Tyrosine Kinases, src-Family
- src Family Tyrosine Kinases
- src Tyrosine Kinases
- Kinases, src Tyrosine
- Tyrosine Kinases, src
- Protein-Tyrosine Kinases, src
- Kinases, src Protein-Tyrosine
- src Protein-Tyrosine Kinases
- src Kinases
- Kinases, src
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Below are MeSH descriptors whose meaning is more general than "src-Family Kinases".
Below are MeSH descriptors whose meaning is more specific than "src-Family Kinases".
This graph shows the total number of publications written about "src-Family Kinases" by people in this website by year, and whether "src-Family Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "src-Family Kinases" by people in Profiles.
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West JD, Carrier EJ, Bloodworth NC, Schroer AK, Chen P, Ryzhova LM, Gladson S, Shay S, Hutcheson JD, Merryman WD. Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension. PLoS One. 2016; 11(2):e0148657.
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Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. Proteomics. 2013 May; 13(10-11):1672-86.
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Sundgren NC, Zhu W, Yuhanna IS, Chambliss KL, Ahmed M, Tanigaki K, Umetani M, Mineo C, Shaul PW. Coupling of Fc? receptor I to Fc? receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function. Circ Res. 2011 Oct 28; 109(10):1132-40.
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West J. Cross talk between Smad, MAPK, and actin in the etiology of pulmonary arterial hypertension. Adv Exp Med Biol. 2010; 661:265-78.
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Tomar A, George SP, Mathew S, Khurana S. Differential effects of lysophosphatidic acid and phosphatidylinositol 4,5-bisphosphate on actin dynamics by direct association with the actin-binding protein villin. J Biol Chem. 2009 Dec 18; 284(51):35278-82.
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Mathew S, George SP, Wang Y, Siddiqui MR, Srinivasan K, Tan L, Khurana S. Potential molecular mechanism for c-Src kinase-mediated regulation of intestinal cell migration. J Biol Chem. 2008 Aug 15; 283(33):22709-22.
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Khurana S, Tomar A, George SP, Wang Y, Siddiqui MR, Guo H, Tigyi G, Mathew S. Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia. Exp Cell Res. 2008 Feb 01; 314(3):530-42.
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Wang Y, Tomar A, George SP, Khurana S. Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration. Am J Physiol Cell Physiol. 2007 May; 292(5):C1775-86.
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Martin-Caraballo M, Dryer SE. Glial cell line-derived neurotrophic factor and target-dependent regulation of large-conductance KCa channels in developing chick lumbar motoneurons. J Neurosci. 2002 Dec 01; 22(23):10201-8.
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