 Cholestanetriol 26-Monooxygenase
"Cholestanetriol 26-Monooxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NAPH-dependent cytochrome P450 enzyme that catalyzes the oxidation of the side chain of sterol intermediates such as the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol.
| Descriptor ID |
D053493
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| MeSH Number(s) |
D08.244.453.915.149 D08.811.682.690.708.170.915.150 D12.776.422.220.453.915.150
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| Concept/Terms |
Cholestanetriol 26-Monooxygenase- Cholestanetriol 26-Monooxygenase
- Cholestanetriol 26 Monooxygenase
- C27-Steroid 26-Hydroxylase
- C27 Steroid 26 Hydroxylase
- Cytochrome P-450 Steroid 27-Hydroxylase
- Cytochrome P 450 Steroid 27 Hydroxylase
- Vitamin D3 25-Hydroxylase
- Vitamin D3 25 Hydroxylase
- Steroid 25-Hydroxylase
- Steroid 25 Hydroxylase
- Steroid 27-Hydroxylase
- Steroid 27 Hydroxylase
- Sterol 26-Hydroxylase
- Sterol 26 Hydroxylase
- Sterol 27-Hydroxylase
- Sterol 27 Hydroxylase
- 5-beta-Cholestane-3-alpha,7-alpha,12-alpha-triol 27-Hydroxylase
- Cytochrome P-450 Sterol 26-Hydroxylase
- Cytochrome P 450 Sterol 26 Hydroxylase
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Below are MeSH descriptors whose meaning is more general than "Cholestanetriol 26-Monooxygenase".
Below are MeSH descriptors whose meaning is more specific than "Cholestanetriol 26-Monooxygenase".
This graph shows the total number of publications written about "Cholestanetriol 26-Monooxygenase" by people in this website by year, and whether "Cholestanetriol 26-Monooxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cholestanetriol 26-Monooxygenase" by people in Profiles.
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Nelson ER, Wardell SE, Jasper JS, Park S, Suchindran S, Howe MK, Carver NJ, Pillai RV, Sullivan PM, Sondhi V, Umetani M, Geradts J, McDonnell DP. 27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology. Science. 2013 Nov 29; 342(6162):1094-8.
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DuSell CD, Nelson ER, Wang X, Abdo J, Mödder UI, Umetani M, Gesty-Palmer D, Javitt NB, Khosla S, McDonnell DP. The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. Endocrinology. 2010 Aug; 151(8):3675-85.
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Goodwin B, Gauthier KC, Umetani M, Watson MA, Lochansky MI, Collins JL, Leitersdorf E, Mangelsdorf DJ, Kliewer SA, Repa JJ. Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):223-8.
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