A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.

Descriptor ID	D054460
MeSH Number(s)	D08.811.913.696.620.682.700.814 D12.644.360.590 D12.776.476.595
Concept/Terms	rho-Associated Kinases rho-Associated Kinases rho Associated Kinases ROK Kinase rho-Kinase rho Kinase ROCK Protein Kinases Protein Kinases, ROCK rho-Associated Coiled-Coil Kinase Coiled-Coil Kinase, rho-Associated rho Associated Coiled Coil Kinase rho-Associated Kinase rho Associated Kinase rho-Associated Kinase 1 rho-Associated Kinase 1 rho Associated Kinase 1 ROCK-I Protein Kinase ROCK I Protein Kinase rho-Associated Kinase beta rho Associated Kinase beta rho-Associated Protein Kinase beta rho Associated Protein Kinase beta p160ROCK rho-Associated Coiled-Coil Containing Protein Kinase 1 rho Associated Coiled Coil Containing Protein Kinase 1 rho-Associated Kinase 2 rho-Associated Kinase 2 rho Associated Kinase 2 ROCK-II Protein Kinase ROCK II Protein Kinase rho-Associated Kinase alpha rho Associated Kinase alpha rho-Associated Protein Kinase alpha rho Associated Protein Kinase alpha p160 rhoA-Binding Kinase ROKalpha p160 rhoA Binding Kinase ROKalpha rho-Associated Coiled-Coil Containing Protein Kinase 2 rho Associated Coiled Coil Containing Protein Kinase 2

Below are MeSH descriptors whose meaning is more general than "rho-Associated Kinases".

Below are MeSH descriptors whose meaning is related to "rho-Associated Kinases".

Below are MeSH descriptors whose meaning is more specific than "rho-Associated Kinases".