 Heterotrimeric GTP-Binding Proteins
"Heterotrimeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.
| Descriptor ID |
D020962
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| MeSH Number(s) |
D08.811.277.040.330.300.200 D12.644.360.375 D12.776.157.325.332 D12.776.476.375 D12.776.543.325
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| Concept/Terms |
Heterotrimeric GTP-Binding Proteins- Heterotrimeric GTP-Binding Proteins
- GTP-Binding Proteins, Heterotrimeric
- Heterotrimeric GTP Binding Proteins
- Heterotrimeric G-Proteins
- G-Proteins, Heterotrimeric
- Heterotrimeric G Proteins
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Below are MeSH descriptors whose meaning is more general than "Heterotrimeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Heterotrimeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Heterotrimeric GTP-Binding Proteins" by people in this website by year, and whether "Heterotrimeric GTP-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 2 | 0 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterotrimeric GTP-Binding Proteins" by people in Profiles.
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Ritchey ER, Zelinka C, Tang J, Liu J, Code KA, Petersen-Jones S, Fischer AJ. Vision-guided ocular growth in a mutant chicken model with diminished visual acuity. Exp Eye Res. 2012 Sep; 102:59-69.
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Ritchey ER, Bongini RE, Code KA, Zelinka C, Petersen-Jones S, Fischer AJ. The pattern of expression of guanine nucleotide-binding protein beta3 in the retina is conserved across vertebrate species. Neuroscience. 2010 Sep 01; 169(3):1376-91.
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Woodroffe PJ, Bridge LJ, King JR, Hill SJ. Modelling the activation of G-protein coupled receptors by a single drug. Math Biosci. 2009 May; 219(1):32-55.
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Cordeaux Y, Ijzerman AP, Hill SJ. Coupling of the human A1 adenosine receptor to different heterotrimeric G proteins: evidence for agonist-specific G protein activation. Br J Pharmacol. 2004 Nov; 143(6):705-14.
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Trivedi M, Marwaha A, Lokhandwala M. Rosiglitazone restores G-protein coupling, recruitment, and function of renal dopamine D1A receptor in obese Zucker rats. Hypertension. 2004 Feb; 43(2):376-82.
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Xiao RP, Zhang SJ, Chakir K, Avdonin P, Zhu W, Bond RA, Balke CW, Lakatta EG, Cheng H. Enhanced G(i) signaling selectively negates beta2-adrenergic receptor (AR)--but not beta1-AR-mediated positive inotropic effect in myocytes from failing rat hearts. Circulation. 2003 Sep 30; 108(13):1633-9.
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Song Q, Schmidt AG, Hahn HS, Carr AN, Frank B, Pater L, Gerst M, Young K, Hoit BD, McConnell BK, Haghighi K, Seidman CE, Seidman JG, Dorn GW, Kranias EG. Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest. 2003 Mar; 111(6):859-67.
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Becker M, Umrani D, Lokhandwala MF, Hussain T. Increased renal angiotensin II AT1 receptor function in obese Zucker rat. Clin Exp Hypertens. 2003 Jan; 25(1):35-47.
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Cordeaux Y, Briddon SJ, Megson AE, McDonnell J, Dickenson JM, Hill SJ. Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A(1) receptor: evidence for signaling pathway-dependent changes in agonist potency and relative intrinsic activity. Mol Pharmacol. 2000 Nov; 58(5):1075-84.
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