 Guanylate Cyclase
"Guanylate Cyclase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
| Descriptor ID |
D006162
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| MeSH Number(s) |
D08.811.520.650.600 D12.644.360.350 D12.776.476.350
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| Concept/Terms |
Guanylate Cyclase- Guanylate Cyclase
- Cyclase, Guanylate
- Guanylyl Cyclase
- Cyclase, Guanylyl
- Inosinate Cyclase
- Cyclase, Inosinate
- Deoxyguanylate Cyclase
- Cyclase, Deoxyguanylate
- Guanyl Cyclase
- Cyclase, Guanyl
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Below are MeSH descriptors whose meaning is more general than "Guanylate Cyclase".
Below are MeSH descriptors whose meaning is more specific than "Guanylate Cyclase".
This graph shows the total number of publications written about "Guanylate Cyclase" by people in this website by year, and whether "Guanylate Cyclase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Guanylate Cyclase" by people in Profiles.
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Zulliger R, Naash MI, Rajala RV, Molday RS, Azadi S. Impaired association of retinal degeneration-3 with guanylate cyclase-1 and guanylate cyclase-activating protein-1 leads to leber congenital amaurosis-1. J Biol Chem. 2015 Feb 06; 290(6):3488-99.
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Tanifum EA, Kots AY, Choi BK, Murad F, Gilbertson SR. Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis. Bioorg Med Chem Lett. 2009 Jun 01; 19(11):3067-71.
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Alzoubi KH, Alkadhi KA. Calmodulin and guanylyl cyclase inhibitors block the in vivo expression of gLTP in sympathetic ganglia from chronically stressed rats. Neurosci Res. 2009 Feb; 63(2):95-9.
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Kots AY, Choi BK, Estrella-Jimenez ME, Warren CA, Gilbertson SR, Guerrant RL, Murad F. Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8440-5.
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