Ubiquitin-Specific Proteases
"Ubiquitin-Specific Proteases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of the peptidase C19 family which regulate signal transduction by removing UBIQUITIN from specific protein substrates via a process known as deubiquitination or deubiquitylation.
| Descriptor ID |
D064570
|
| MeSH Number(s) |
D08.811.277.656.300.887
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Specific Proteases".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Specific Proteases".
This graph shows the total number of publications written about "Ubiquitin-Specific Proteases" by people in this website by year, and whether "Ubiquitin-Specific Proteases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ubiquitin-Specific Proteases" by people in Profiles.
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Kathman SG, Xu Z, Statsyuk AV. A fragment-based method to discover irreversible covalent inhibitors of cysteine proteases. J Med Chem. 2014 Jun 12; 57(11):4969-74.
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Mistry H, Hsieh G, Buhrlage SJ, Huang M, Park E, Cuny GD, Galinsky I, Stone RM, Gray NS, D'Andrea AD, Parmar K. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec; 12(12):2651-62.