 Adenosine
"Adenosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
| Descriptor ID |
D000241
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| MeSH Number(s) |
D03.438.759.590.138 D13.570.583.138 D13.570.800.096
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adenosine".
Below are MeSH descriptors whose meaning is more specific than "Adenosine".
This graph shows the total number of publications written about "Adenosine" by people in this website by year, and whether "Adenosine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 3 | 0 | 3 | | 1982 | 1 | 0 | 1 | | 1983 | 1 | 1 | 2 | | 1984 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1987 | 0 | 2 | 2 | | 1988 | 2 | 1 | 3 | | 1992 | 0 | 2 | 2 | | 1993 | 2 | 2 | 4 | | 1994 | 2 | 3 | 5 | | 1995 | 0 | 3 | 3 | | 1996 | 1 | 2 | 3 | | 1997 | 0 | 1 | 1 | | 1998 | 2 | 1 | 3 | | 1999 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Adenosine" by people in Profiles.
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Stoddart LA, Vernall AJ, Briddon SJ, Kellam B, Hill SJ. Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist. Neuropharmacology. 2015 Nov; 98:68-77.
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Stoddart LA, Kellam B, Briddon SJ, Hill SJ. Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization. Br J Pharmacol. 2014 Aug; 171(16):3827-44.
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May LT, Bridge LJ, Stoddart LA, Briddon SJ, Hill SJ. Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics. FASEB J. 2011 Oct; 25(10):3465-76.
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Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Detrimental effects of adenosine signaling in sickle cell disease. Nat Med. 2011 Jan; 17(1):79-86.
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May LT, Self TJ, Briddon SJ, Hill SJ. The effect of allosteric modulators on the kinetics of agonist-G protein-coupled receptor interactions in single living cells. Mol Pharmacol. 2010 Sep; 78(3):511-23.
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Cordeaux Y, Briddon SJ, Alexander SP, Kellam B, Hill SJ. Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells. FASEB J. 2008 Mar; 22(3):850-60.
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Middleton RJ, Briddon SJ, Cordeaux Y, Yates AS, Dale CL, George MW, Baker JG, Hill SJ, Kellam B. New fluorescent adenosine A1-receptor agonists that allow quantification of ligand-receptor interactions in microdomains of single living cells. J Med Chem. 2007 Feb 22; 50(4):782-93.
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Briddon SJ, Middleton RJ, Yates AS, George MW, Kellam B, Hill SJ. Application of fluorescence correlation spectroscopy to the measurement of agonist binding to a G-protein coupled receptor at the single cell level. Faraday Discuss. 2004; 126:197-207; discussion 245-54.
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Hill KJ, Webber AC, Hill SJ. A role of protein kinase C mu in signalling from the human adenosine A1 receptor to the nucleus. Br J Pharmacol. 2003 Jun; 139(4):721-32.
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Macaluso C, Frishman LJ, Frueh B, Kaelin-Lang A, Onoe S, Niemeyer G. Multiple effects of adenosine in the arterially perfused mammalian eye. Possible mechanisms for the neuroprotective function of adenosine in the retina. Doc Ophthalmol. 2003 Jan; 106(1):51-9.
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