 Antigens, Polyomavirus Transforming
"Antigens, Polyomavirus Transforming" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.
| Descriptor ID |
D000952
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| MeSH Number(s) |
D12.776.624.664.520.090 D12.776.964.700.090 D23.050.285.062.090 D23.050.327.062.090
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| Concept/Terms |
Antigens, Polyomavirus Transforming- Antigens, Polyomavirus Transforming
- Polyomavirus Tumor Antigens
- Antigens, Polyomavirus Tumor
- Tumor Antigens, Polyomavirus
- Polyomavirus Transforming Antigens
- Transforming Antigens, Polyomavirus
SV40 T Proteins- SV40 T Proteins
- Proteins, SV40 T
- T Proteins, SV40
- SV40 T Antigens
- Antigens, SV40 T
- T Antigens, SV40
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Below are MeSH descriptors whose meaning is more general than "Antigens, Polyomavirus Transforming".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Neoplasm Proteins [D12.776.624]
- Oncogene Proteins [D12.776.624.664]
- Oncogene Proteins, Viral [D12.776.624.664.520]
- Antigens, Polyomavirus Transforming [D12.776.624.664.520.090]
- Viral Proteins [D12.776.964]
- Oncogene Proteins, Viral [D12.776.964.700]
- Antigens, Polyomavirus Transforming [D12.776.964.700.090]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Neoplasm [D23.050.285]
- Antigens, Viral, Tumor [D23.050.285.062]
- Antigens, Polyomavirus Transforming [D23.050.285.062.090]
- Antigens, Viral [D23.050.327]
- Antigens, Viral, Tumor [D23.050.327.062]
- Antigens, Polyomavirus Transforming [D23.050.327.062.090]
Below are MeSH descriptors whose meaning is more specific than "Antigens, Polyomavirus Transforming".
This graph shows the total number of publications written about "Antigens, Polyomavirus Transforming" by people in this website by year, and whether "Antigens, Polyomavirus Transforming" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2008 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antigens, Polyomavirus Transforming" by people in Profiles.
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Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL. Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2814-9.
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Otteson DC, Phillips MJ. A conditional immortalized mouse muller glial cell line expressing glial and retinal stem cell genes. Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5991-6000.
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Al-Ubaidi MR, Matsumoto H, Kurono S, Singh A. Proteomics profiling of the cone photoreceptor cell line, 661W. Adv Exp Med Biol. 2008; 613:301-11.
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Kanan Y, Jacobi AK, Sawyer K, Mannel DS, Tink JT, Al-Ubaidi MR. An in-vivo assay to identify compounds protective against light induced apoptosis. Adv Exp Med Biol. 2008; 613:61-7.
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Lu X, Arbiser JL, West J, Hoedt-Miller M, Sheridan A, Govindarajan B, Harral JW, Rodman DM, Fouty B. Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells. Am J Pathol. 2004 Nov; 165(5):1613-20.
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Tan E, Ding XQ, Saadi A, Agarwal N, Naash MI, Al-Ubaidi MR. Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice. Invest Ophthalmol Vis Sci. 2004 Mar; 45(3):764-8.
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Roque RS, Rosales AA, Jingjing L, Agarwal N, Al-Ubaidi MR. Retina-derived microglial cells induce photoreceptor cell death in vitro. Brain Res. 1999 Jul 31; 836(1-2):110-9.
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Saphire AC, Bark SJ, Gerace L. All four homochiral enantiomers of a nuclear localization sequence derived from c-Myc serve as functional import signals. J Biol Chem. 1998 Nov 06; 273(45):29764-9.
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Al-Ubaidi MR, Mangini NJ, Quiambao AB, Myers KM, Abler AS, Chang CJ, Tso MO, Butel JS, Hollyfield JG. Unscheduled DNA replication precedes apoptosis of photoreceptors expressing SV40 T antigen. Exp Eye Res. 1997 Apr; 64(4):573-85.
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Marcus DM, Lasudry JG, Carpenter JL, Windle J, Howes KA, al-Ubaidi MR, Baehr W, Overbeek PA, Font RL, Albert DM. Trilateral tumors in four different lines of transgenic mice expressing SV40 T-antigen. Invest Ophthalmol Vis Sci. 1996 Feb; 37(2):392-6.
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